التفاصيل البيبلوغرافية
| العنوان: |
PhIP-Seq: methods, applications and challenges |
| المؤلفون: |
Ziru Huang, Samarappuli Mudiyanselage Savini Gunarathne, Wenwen Liu, Yuwei Zhou, Yuqing Jiang, Shiqi Li, Jian Huang |
| المصدر: |
Frontiers in Bioinformatics, Vol 4 (2024) |
| بيانات النشر: |
Frontiers Media S.A., 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Computer applications to medicine. Medical informatics |
| مصطلحات موضوعية: |
phage, PhIP-Seq, antibody, immunity, biotechnological applications, Computer applications to medicine. Medical informatics, R858-859.7 |
| الوصف: |
Phage-immunoprecipitation sequencing (PhIP-Seq) technology is an innovative, high-throughput antibody detection method. It enables comprehensive analysis of individual antibody profiles. This technology shows great potential, particularly in exploring disease mechanisms and immune responses. Currently, PhIP-Seq has been successfully applied in various fields, such as the exploration of biomarkers for autoimmune diseases, vaccine development, and allergen detection. A variety of bioinformatics tools have facilitated the development of this process. However, PhIP-Seq technology still faces many challenges and has room for improvement. Here, we review the methods, applications, and challenges of PhIP-Seq and discuss its future directions in immunological research and clinical applications. With continuous progress and optimization, PhIP-Seq is expected to play an even more important role in future biomedical research, providing new ideas and methods for disease prevention, diagnosis, and treatment. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2673-7647 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fbinf.2024.1424202/full; https://doaj.org/toc/2673-7647 |
| DOI: |
10.3389/fbinf.2024.1424202 |
| URL الوصول: |
https://doaj.org/article/f8ab76fca97b4ba7b6c73b00c0d68da3 |
| رقم الانضمام: |
edsdoj.f8ab76fca97b4ba7b6c73b00c0d68da3 |
| قاعدة البيانات: |
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