Academic Journal
Effects of Posture and Walking on Tibial Vascular Hemodynamics Before and After 14 Days of Head‐Down Bed Rest
العنوان: | Effects of Posture and Walking on Tibial Vascular Hemodynamics Before and After 14 Days of Head‐Down Bed Rest |
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المؤلفون: | Eric T Hedge, Laurence Vico, Richard L Hughson, Carmelo J Mastrandrea |
المصدر: | JBMR Plus, Vol 7, Iss 7, Pp n/a-n/a (2023) |
بيانات النشر: | Oxford University Press, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Orthopedic surgery LCC:Diseases of the musculoskeletal system |
مصطلحات موضوعية: | HEAD‐DOWN BED REST, NEAR INFRARED SPECTROSCOPY (NIRS), SKELETAL VASCULAR SUPPLY, TIBIAL HEMODYNAMICS, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935 |
الوصف: | ABSTRACT Human skeletal hemodynamics remain understudied. Neither assessments in weight‐bearing bones during walking nor following periods of immobility exist, despite knowledge of altered nutrient‐artery characteristics after short‐duration unloading in rodents. We studied 12 older adults (8 females, aged 59 ± 3 years) who participated in ambulatory near‐infrared spectroscopy (NIRS) assessments of tibial hemodynamics before (PRE) and after (POST) 14 days of head‐down bed rest (HDBR), with most performing daily resistance and aerobic exercise countermeasures during HDBR. Continual simultaneous NIRS recordings were acquired over the proximal anteromedial tibial prominence of the right lower leg and ipsilateral lateral head of the gastrocnemius muscle during supine rest, walking, and standing. During 10 minutes of walking, desaturation kinetics in the tibia were slower (time to 95% nadir values 125.4 ± 56.8 s versus 55.0 ± 30.1 s, p = 0.0014). Tibial tissue saturation index (TSI) immediately fell (−9.9 ± 4.55) and did not completely recover by the end of 10 minutes of walking (−7.4 ± 6.7%, p = 0.027). Upon standing, total hemoglobin (tHb) kinetics were faster in the tibia (p |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2473-4039 |
Relation: | https://doaj.org/toc/2473-4039 |
DOI: | 10.1002/jbm4.10756 |
URL الوصول: | https://doaj.org/article/f85ece45f64d458cb55b443d1b7e0960 |
رقم الانضمام: | edsdoj.f85ece45f64d458cb55b443d1b7e0960 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 24734039 |
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DOI: | 10.1002/jbm4.10756 |