Academic Journal
Oxidative stress and endothelial dysfunction correction with ACE inhibitor therapy in patients with myocardial infarction and Type 2 diabetes mellitus
| العنوان: | Oxidative stress and endothelial dysfunction correction with ACE inhibitor therapy in patients with myocardial infarction and Type 2 diabetes mellitus |
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| المؤلفون: | V. S. Zadionchenko, K. S. Leksina, N. Yu. Timofeeva, G. G. Shekhyan, M. A. Mironova, T. M. Terekhova |
| المصدر: | Российский кардиологический журнал, Vol 0, Iss 5, Pp 40-45 (2008) |
| بيانات النشر: | «FIRMA «SILICEA» LLC, 2008. |
| سنة النشر: | 2008 |
| المجموعة: | LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | myocardial infarction, type 2 diabetes mellitus, oxidative stress, endothelial dysfunction, corrective potential, zofenopril, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | In total, 25 patients with acute myocardial infarction (MI) and 25 patients with MI and Type 2 diabetes mellitus (DM-2) received an ACE inhibitor zofenopril (zocardis) for 6 months, as a part of their basis therapy. Lipid peroxidation and antioxidant system dynamics, endogenous cytoprotective mechanisms - NO and HSP70 stress proteins - were assessed during first 24 hours after hospitalization, as well as 1 and 6 months after MI. Long-term zofenopril therapy was associated with reduced levels of free-radical lipid peroxidation, due to protective antioxidant enzyme activation and increase in serum total antioxidant activity. The medication also improved the parameters ofprotective HSP70 system and endothelial function. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 1560-4071 2618-7620 |
| Relation: | https://russjcardiol.elpub.ru/jour/article/view/1624; https://doaj.org/toc/1560-4071; https://doaj.org/toc/2618-7620 |
| URL الوصول: | https://doaj.org/article/f84f153a67f542bf9ccb8f6547a92a67 |
| رقم الانضمام: | edsdoj.f84f153a67f542bf9ccb8f6547a92a67 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 15604071 26187620 |
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