التفاصيل البيبلوغرافية
العنوان: |
A low-glucose eating pattern is associated with improvements in glycemic variability among women at risk for postmenopausal breast cancer: an exploratory analysis |
المؤلفون: |
Michelle R. Jospe, Yue Liao, Erin D. Giles, Barry I. Hudson, Joyce M. Slingerland, Susan M. Schembre |
المصدر: |
Frontiers in Nutrition, Vol 11 (2024) |
بيانات النشر: |
Frontiers Media S.A., 2024. |
سنة النشر: |
2024 |
المجموعة: |
LCC:Nutrition. Foods and food supply |
مصطلحات موضوعية: |
glucose-guided eating, glycemic control, blood glucose self-monitoring, continuous glucose monitoring, food intake regulation, Nutrition. Foods and food supply, TX341-641 |
الوصف: |
BackgroundHigh glycemic variability (GV) is a biomarker of cancer risk, even in the absence of diabetes. The emerging concept of chrononutrition suggests that modifying meal timing can favorably impact metabolic risk factors linked to diet-related chronic disease, including breast cancer. Here, we examined the potential of eating when glucose levels are near personalized fasting thresholds (low-glucose eating, LGE), a novel form of timed-eating, to reduce GV in women without diabetes, who are at risk for postmenopausal breast cancer.MethodsIn this exploratory analysis of our 16-week weight loss randomized controlled trial, we included 17 non-Hispanic, white, postmenopausal women (average age = 60.7 ± 5.8 years, BMI = 34.5 ± 6.1 kg/m2, HbA1c = 5.7 ± 0.3%). Participants were those who, as part of the parent study, provided 3–7 days of blinded, continuous glucose monitoring data and image-assisted, timestamped food records at weeks 0 and 16. Pearson’s correlation and multivariate regression were used to assess associations between LGE and GV, controlling for concurrent weight changes.ResultsIncreases in LGE were associated with multiple unfavorable measures of GV including reductions in CGM glucose mean, CONGA, LI, J-Index, HBGI, ADDR, and time spent in a severe GV pattern (r = −0.81 to −0.49; ps |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
2296-861X |
Relation: |
https://www.frontiersin.org/articles/10.3389/fnut.2024.1301427/full; https://doaj.org/toc/2296-861X |
DOI: |
10.3389/fnut.2024.1301427 |
URL الوصول: |
https://doaj.org/article/f821ad2a22324afbade2e58a8372c7e3 |
رقم الانضمام: |
edsdoj.f821ad2a22324afbade2e58a8372c7e3 |
قاعدة البيانات: |
Directory of Open Access Journals |