Academic Journal

Age-specific ASPECTS atlas of Chinese subjects across different age groups for assessing acute ischemic stroke

التفاصيل البيبلوغرافية
العنوان: Age-specific ASPECTS atlas of Chinese subjects across different age groups for assessing acute ischemic stroke
المؤلفون: Qi Sun, Guan Wang, Jinzhu Yang, Yimo Zhou, Yuliang Yuan, Yan Huang, Ziyu Fu
المصدر: Scientific Data, Vol 11, Iss 1, Pp 1-11 (2024)
بيانات النشر: Nature Portfolio, 2024.
سنة النشر: 2024
المجموعة: LCC:Science
مصطلحات موضوعية: Science
الوصف: Abstract The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is a valuable and easy-to-use method for assessing acute ischemic stroke. It aids in identifying suitable candidates for thrombolytic therapies and evaluating treatment effectiveness. However, ASPECTS evaluation primarily relies on visual observation in current clinical practice, lacking a common standardized space. Additionally, different doctors may have varying clinical experiences, leading to a poor inter-reader agreement and potential errors in the final ASPECTS scoring. To address these issues and fill in the absence of a publicly available ASPECTS atlas, this work constructs age-specific Chinese ASPECTS atlases based on non-contrast computed tomography images of 281 healthy subjects across different age groups. Images of different age groups are warped into respective common averaged spaces, where the average intensity atlases are computed. More importantly, 10 ASPECTS regions can be obtained during this process. We develop an automated ASPECTS region mapping pipeline and collect an independent dataset to validate our atlas. The results prove that the age-specific ASPECTS atlas is of great promise in clinical availability.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2052-4463
Relation: https://doaj.org/toc/2052-4463
DOI: 10.1038/s41597-024-03973-y
URL الوصول: https://doaj.org/article/f7cf3f7ecc794d79937cc46e5b2addd4
رقم الانضمام: edsdoj.f7cf3f7ecc794d79937cc46e5b2addd4
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20524463
DOI:10.1038/s41597-024-03973-y