التفاصيل البيبلوغرافية
| العنوان: |
TAp63 contributes to sexual dimorphism in POMC neuron functions and energy homeostasis |
| المؤلفون: |
Chunmei Wang, Yanlin He, Pingwen Xu, Yongjie Yang, Kenji Saito, Yan Xia, Xiaofeng Yan, Antentor Hinton Jr, Chunling Yan, Hongfang Ding, Likai Yu, Gang Shu, Rajat Gupta, Qi Wu, Qingchun Tong, William R. Lagor, Elsa R. Flores, Yong Xu |
| المصدر: |
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
| بيانات النشر: |
Nature Portfolio, 2018. |
| سنة النشر: |
2018 |
| المجموعة: |
LCC:Science |
| مصطلحات موضوعية: |
Science |
| الوصف: |
Sexual dimorphism exists in a number of physiological processes, including energy homeostasis. Here, the authors show that pro-opiomelanocortin neurons in female mice fire more rapidly than males, and that deletion of the transcription TAp63 leads to a reduced neuronal firing rate and a male-like susceptibility to diet-induced obesity. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-018-03796-7 |
| URL الوصول: |
https://doaj.org/article/f7cdf5faab7a4548b6351ebcba1722a5 |
| رقم الانضمام: |
edsdoj.f7cdf5faab7a4548b6351ebcba1722a5 |
| قاعدة البيانات: |
Directory of Open Access Journals |
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