التفاصيل البيبلوغرافية
| العنوان: |
Predictive Value of Serum Creatinine, Blood Urea Nitrogen, Uric Acid, and β2-Microglobulin in the Evaluation of Acute Kidney Injury after Orthotopic Liver Transplantation |
| المؤلفون: |
Hai-Yang Lu, Xin-Yu Ning, Ying-Qi Chen, Shu-Jun Han, Ping Chi, Sai-Nan Zhu, Yun Yue |
| المصدر: |
Chinese Medical Journal, Vol 131, Iss 9, Pp 1059-1066 (2018) |
| بيانات النشر: |
Wolters Kluwer, 2018. |
| سنة النشر: |
2018 |
| المجموعة: |
LCC:Medicine |
| مصطلحات موضوعية: |
Acute Kidney Injury, Blood Urea Nitrogen, Creatinine, Liver Transplantation, Uric Acid, β2-Microglobulin, Medicine |
| الوصف: |
Background: As a major complication after orthotopic liver transplantation (OLT), the occurrence of acute kidney injury (AKI) is frequently defined by serum creatinine (Cr); however, the accuracy of commonly used blood urea nitrogen (BUN), uric acid (UA), and β2-microglobulin (β2-MG) remains to be explored. This retrospective study compared the accuracy of these parameters for post-OLT AKI evaluation. Methods: Patients who underwent OLT in three centers between July 2003 and December 2013 were enrolled. The postoperative AKI group was diagnosed by the Kidney Disease Improving Global Outcomes (KDIGO) criteria and classified by stage. Measurement data were analyzed using the t-test or Wilcoxon rank-sum test; enumerated data were analyzed using the Chi-square test or Fisher's exact test. Diagnostic reliability and predictive accuracy were evaluated using receiver operating characteristic (ROC) curve analysis. Results: This study excluded 976 cases and analyzed 697 patients (578 men and 119 women); the post-OLT AKI incidence was 0.409. Compared with the no-AKI group, the AKI group showed very significant differences in Model for End-stage Liver Disease score (14.74 ± 9.91 vs. 11.07 ± 9.54, Z = 5.404; P < 0.001), hepatic encephalopathy (45 [15.8%] vs. 30 [7.3%], χ2 = 12.699; P < 0.001), hemofiltration (28 [9.8%] vs. 0 [0.0%], χ2 = 42.171; P < 0.001), and 28-day mortality (23 [8.1%] vs. 9 [2.2%], χ2 = 13.323; P |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
0366-6999 |
| Relation: |
http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=9;spage=1059;epage=1066;aulast=Lu; https://doaj.org/toc/0366-6999 |
| DOI: |
10.4103/0366-6999.230726 |
| URL الوصول: |
https://doaj.org/article/ef66c4092e87443d9f5585ac1daee47f |
| رقم الانضمام: |
edsdoj.f66c4092e87443d9f5585ac1daee47f |
| قاعدة البيانات: |
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