التفاصيل البيبلوغرافية
| العنوان: |
Uncleavable Nup98–Nup96 is functional in the fission yeastSchizosaccharomyces pombe |
| المؤلفون: |
Haruhiko Asakawa, Chie Mori, Chizuru Ohtsuki, Masaaki Iwamoto, Yasushi Hiraoka, Tokuko Haraguchi |
| المصدر: |
FEBS Open Bio, Vol 5, Iss 1, Pp 508-514 (2015) |
| بيانات النشر: |
Wiley, 2015. |
| سنة النشر: |
2015 |
| المجموعة: |
LCC:Biology (General) |
| مصطلحات موضوعية: |
Nucleoporins, Nuclear pore complex, FG nup, Nup107-160 complex, Alternative splicing, Fission yeast, Biology (General), QH301-705.5 |
| الوصف: |
Essential nucleoporins Nup98 and Nup96 are coded by a single open reading frame, and produced by autopeptidase cleavage. The autocleavage site of Nup98–Nup96 is highly conserved in a wide range of organisms. To understand the importance of autocleavage, we examined a mutant that produces the Nup98–Nup96 joint molecule as a sole protein product of thenup189+ gene in the fission yeastSchizosaccharomyces pombe. Cells expressing only the joint molecule were found to be viable. This result indicates that autocleavage of Nup98–Nup96 is dispensable for cell growth, at least under normal culture conditions inS. pombe. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2211-5463 |
| Relation: |
https://doaj.org/toc/2211-5463 |
| DOI: |
10.1016/j.fob.2015.06.004 |
| URL الوصول: |
https://doaj.org/article/f5884c3021f8485f8e1b09c0cbeb5ad8 |
| رقم الانضمام: |
edsdoj.f5884c3021f8485f8e1b09c0cbeb5ad8 |
| قاعدة البيانات: |
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