التفاصيل البيبلوغرافية
| العنوان: |
Clinical effect of lymphocyte immunotherapy on patients with unexplained recurrent spontaneous abortion |
| المؤلفون: |
Sudong Liu, Xiaodong Gu, Ruiqiang Weng |
| المصدر: |
Immunity, Inflammation and Disease, Vol 9, Iss 4, Pp 1272-1278 (2021) |
| بيانات النشر: |
Wiley, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Immunologic diseases. Allergy |
| مصطلحات موضوعية: |
blocking antibody (BA), live birth rate, lymphocyte immunotherapy (LIT), unexplained recurrent spontaneous abortion (URSA), Immunologic diseases. Allergy, RC581-607 |
| الوصف: |
Abstract Introduction Lymphocyte immunotherapy (LIT) is believed to be a viable treatment for unexplained recurrent spontaneous abortion (URSA), but its effect remains controversial. This study aims to investigate the clinical effect of LIT in patients with URSA and clarify the factors that may influence the outcome of LIT. Methods This study included a total of 704 URSA patients, of which 444 patients accepted LIT treatment. URSA patients that did not accept LIT served as control group. Clinical characteristics were collected and analyzed between LIT and control group. The blocking antibody was tested before and after LIT. The outcome of LIT treatment was recorded. Logistic regression analysis was applied to evaluate the independent predictors of LIT success. Results After LIT treatment, 77.9% (346/444) of USRA patients turned to BA positive, and the conversion rate elevated with increased LIT (p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2050-4527 |
| Relation: |
https://doaj.org/toc/2050-4527 |
| DOI: |
10.1002/iid3.474 |
| URL الوصول: |
https://doaj.org/article/f56433f4d85b4e2ab3a9d3eb2ba68e6c |
| رقم الانضمام: |
edsdoj.f56433f4d85b4e2ab3a9d3eb2ba68e6c |
| قاعدة البيانات: |
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