Academic Journal
A Comparative Study between Oxcarbazepine and Gabapentin Regarding Therapeutic Efficiency and Tolerability in the Treatment of Trigeminal Neuralgia
| العنوان: | A Comparative Study between Oxcarbazepine and Gabapentin Regarding Therapeutic Efficiency and Tolerability in the Treatment of Trigeminal Neuralgia |
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| المؤلفون: | Fakir Mohan Debta, Anil G Ghom, Jigna S Shah, Priyanka Debta |
| المصدر: | Journal of Indian Academy of Oral Medicine and Radiology, Vol 22, Iss 1, Pp 10-17 (2010) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2010. |
| سنة النشر: | 2010 |
| المجموعة: | LCC:Dentistry LCC:Medical physics. Medical radiology. Nuclear medicine |
| مصطلحات موضوعية: | TN, facial pain, Oxcarbazepine, gabapentin, Dentistry, RK1-715, Medical physics. Medical radiology. Nuclear medicine, R895-920 |
| الوصف: | Trigerninal neuralgia is a relapsing and remittent disorder is best symptomatically treated by medical treatment out of which carbamazepine thought to be a diagnostic drug marker of trigeminal neuralgia, has often undesirable side effects and sometimes ineffective, limiting its usage, thus search for more effective drug with lesser side effect is still on. Recently two newer anticonvulsant oxcarbazepine (OXC) a ketoderivative of carbamazepine and gabapentin (GBP) has been trailed in trigeminal neuralgia in different open clinical trial as monotherapy with encouraging results. These drugs have convenient dosage and surprisingly fewer side effects. These facts that trigeminal neuralgia responds to newer anticonvulsant (oxcarbazepine, gabapentin) in a better perspective, enabled me to conduct the present clinical trial on 54 patients (both in newly diagnosed TN patient and refractive patient) of trigeminal neuralgia who were made two randomized group for separate monotherapy study for a period of six months. The therapeutic effect of OXC and gabapentin (GBP) in relation to reduction in number of attacks of pain and severity of pain were evaluated. All the scoring data showed OXC is more therapeutic efficacious cost-effective and well-tolerated profile than gabapentin and an emerging as a drug for treatment of TN in both new and refractive patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0972-1363 0975-1572 |
| Relation: | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2010;volume=22;issue=1;spage=10;epage=17;aulast=Debta;type=0; https://doaj.org/toc/0972-1363; https://doaj.org/toc/0975-1572 |
| URL الوصول: | https://doaj.org/article/f52e840f5ab646f3abb83186dae0f854 |
| رقم الانضمام: | edsdoj.f52e840f5ab646f3abb83186dae0f854 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 09721363 09751572 |
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