Academic Journal
Subjective vs informant-reported cognitive complaints have differential clinical significance in covert cerebral small vessel disease
| العنوان: | Subjective vs informant-reported cognitive complaints have differential clinical significance in covert cerebral small vessel disease |
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| المؤلفون: | Anne Arola, Hanna M. Laakso, Heidi Heinonen, Johanna Pitkänen, Matti Ahlström, Juha Lempiäinen, Teemu Paajanen, Jussi Virkkala, Juha Koikkalainen, Jyrki Lötjönen, Antti Korvenoja, Susanna Melkas, Hanna Jokinen |
| المصدر: | Cerebral Circulation - Cognition and Behavior, Vol 5, Iss , Pp 100182- (2023) |
| بيانات النشر: | Elsevier, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Specialties of internal medicine LCC:Neurosciences. Biological psychiatry. Neuropsychiatry |
| مصطلحات موضوعية: | Cerebral small vessel disease, White matter hyperintensities, Mild cognitive impairment, Cognition, Awareness of cognitive impairment, Subjective cognitive complaints, Specialties of internal medicine, RC581-951, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
| الوصف: | Objective: Subjective cognitive complaints are common in patients with cerebral small vessel disease (cSVD), yet their relationship with informant evaluations, objective cognitive functions and severity of brain changes are poorly understood. We studied the associations of subjective and informant reports with findings from comprehensive neuropsychological assessment and brain MRI. Method: In the Helsinki SVD Study, 152 older adults with varying degrees of white matter hyperintensities (WMH) but without stroke or dementia were classified as having normal cognition or mild cognitive impairment (MCI) based on neuropsychological criteria. The measures also included continuous domain scores for memory and executive functions. Cognitive complaints were evaluated with the subjective and informant versions of the Prospective and Retrospective Memory Questionnaire (PRMQ) and Dysexecutive Questionnaire (DEX); functional abilities with the Amsterdam Instrumental Activities of Daily Living Questionnaire (A-IADL); and depressive symptoms with the Geriatric Depression Scale (GDS-15). Results: Subjective cognitive complaints correlated significantly with informant reports (r=0.40–0.50, p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2666-2450 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2666245023000260; https://doaj.org/toc/2666-2450 |
| DOI: | 10.1016/j.cccb.2023.100182 |
| URL الوصول: | https://doaj.org/article/f270709120a2423b9ad852268bb02662 |
| رقم الانضمام: | edsdoj.f270709120a2423b9ad852268bb02662 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 26662450 |
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| DOI: | 10.1016/j.cccb.2023.100182 |