التفاصيل البيبلوغرافية
| العنوان: |
Pattern and clinical management of penile cancer in Rwanda |
| المؤلفون: |
E. Ngendahayo, M. Nzayirambaho, A. Bonane, G.A. Gasana, R. Ssebuufu, F. Umurangwa, E. Muhawenimana, A. Nyirimodoka, I. Nzeyimana, B. Rugwizangoga, T.Z. Muvunyi, E. Musoni, S. Bwogi, T. Hategekimana, R. Kalengayi, E. Rwamasirabo |
| المصدر: |
African Journal of Urology, Vol 24, Iss 4, Pp 274-281 (2018) |
| بيانات النشر: |
SpringerOpen, 2018. |
| سنة النشر: |
2018 |
| المجموعة: |
LCC:Diseases of the genitourinary system. Urology |
| مصطلحات موضوعية: |
Diseases of the genitourinary system. Urology, RC870-923 |
| الوصف: |
Introduction: Penile cancer is rare in developed countries but has a high prevalence in some developing countries. Surgery includes inguinal lymphadenectomy, which remains the mainstay treatment of the disease. Objective: This study reports on the epidemiological profile of penile cancer and clinical management options in Rwanda. Patients and methods: From January 2015 to June 2016, a multicenter cross-sectional, prospective cohort study was conducted involving all male patients presenting with penile cancer after two national radio campaigns and a Ministry of Health instruction to all district hospitals. All patients with positive biopsy were included. Surgical treatment aligned with published guidelines. Clinical characteristics, surgery, pathology, and early follow-up data were collected. Results: Over 18 consecutive months, 30 male patients were enrolled. The mean age was 60 years [range 33–83]. All patients were uncircumcised before symptom onset; 50% had phimosis and 20% were HIV-positive. The estimated prevalence of penile cancer in Rwanda was 0.37 per 100,000 men. At presentation, 96.7% of patients had a T2-4 disease and 43.3% were with clinically non-palpable inguinal lymph nodes (cNO). After penectomy, bilateral inguinal lymphadenectomy was performed in 10 (33.3%) patients (modified and radical in 16 and 4 limbs, respectively). Complications included surgical site infection (10%), lymphocele (10%), urethral meatus stenosis (6.7%), skin necrosis (3.3%) and two (6.7%) patients with metastatic disease died in hospital. Conclusion: Penile cancer is a rare but significant disease in Rwanda. Patients present with advanced disease. After treatment of the primary tumor, modified inguinal lymphadenectomy appears to be a safe method of cure and staging for patients with clinically impalpable inguinal lymph nodes. Our early results provide a compelling insight into this rare but serious disease. Keywords: Penile cancer, Penectomy, Inguinal lymph node dissection, Pelvic lymphadenectomy, Rwanda |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1110-5704 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1110570418300778; https://doaj.org/toc/1110-5704 |
| DOI: |
10.1016/j.afju.2018.07.001 |
| URL الوصول: |
https://doaj.org/article/af18b106a0ec4109b49a072582fe1ed9 |
| رقم الانضمام: |
edsdoj.f18b106a0ec4109b49a072582fe1ed9 |
| قاعدة البيانات: |
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