Academic Journal

Genomic Epidemiology of Salmonella Infantis in Ecuador: From Poultry Farms to Human Infections

التفاصيل البيبلوغرافية
العنوان: Genomic Epidemiology of Salmonella Infantis in Ecuador: From Poultry Farms to Human Infections
المؤلفون: Lorena Mejía, José Luis Medina, Rosa Bayas, Carolina Satan Salazar, Fernando Villavicencio, Sonia Zapata, Jorge Matheu, Jaap A. Wagenaar, Fernando González-Candelas, Christian Vinueza-Burgos
المصدر: Frontiers in Veterinary Science, Vol 7 (2020)
بيانات النشر: Frontiers Media S.A., 2020.
سنة النشر: 2020
المجموعة: LCC:Veterinary medicine
مصطلحات موضوعية: Salmonella Infantis, ST32, broiler, WGS, Ecuador, megaplasmid, Veterinary medicine, SF600-1100
الوصف: Salmonella enterica is one of the most important foodborne pathogens around the world. In the last years, S. enterica serovar Infantis has become an important emerging pathogen in many countries, often as multidrug resistant clones. To understand the importance of S. enterica in the broiler industry in Ecuador, we performed a study based on phenotypic and WGS data of isolates from poultry farms, chicken carcasses and humans. We showed a high prevalence of S. enterica in poultry farms (41.4%) and chicken carcasses (55.5%), but a low prevalence (1.98%) in human samples. S. Infantis was shown to be the most prevalent serovar with a 98.2, 97.8, and 50% in farms, foods, and humans, respectively, presenting multidrug resistant patterns. All sequenced S. Infantis isolates belonged to ST32. For the first time, a pESI-related megaplasmid was identified in Ecuadorian samples. This plasmid contains genes of antimicrobial resistance, virulence factors, and environmental stress tolerance. Genomic analysis showed a low divergence of S. Infantis strains in the three analyzed components. The results from this study provide important information about genetic elements that may help understand the molecular epidemiology of S. Infantis in Ecuador.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2297-1769
Relation: https://www.frontiersin.org/article/10.3389/fvets.2020.547891/full; https://doaj.org/toc/2297-1769
DOI: 10.3389/fvets.2020.547891
URL الوصول: https://doaj.org/article/f1037adf54114e03be3b2d2626b9b793
رقم الانضمام: edsdoj.f1037adf54114e03be3b2d2626b9b793
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22971769
DOI:10.3389/fvets.2020.547891