التفاصيل البيبلوغرافية
| العنوان: |
Pig embryonic stem cell line with porcine-specific OCT4 upstream region based dual reporter system |
| المؤلفون: |
Seung-Hun Kim, Kwang-Hwan Choi, Jinsol Jeong, Mingyun Lee, Dong-Kyung Lee, Jong-Nam Oh, Gyeong Cheol Choe, Du-Min Go, Dae-Yong Kim, Chang-Kyu Lee |
| المصدر: |
Stem Cell Research, Vol 57, Iss , Pp 102609- (2021) |
| بيانات النشر: |
Elsevier, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Biology (General) |
| مصطلحات موضوعية: |
Biology (General), QH301-705.5 |
| الوصف: |
Here, we report pig embryonic stem cells (ESCs) originating from parthenogenetic blastocysts which were developed from 2-cell embryos micro-injected with porcine OCT4 reporter system cultured in previous reported chemically defined culture media. The ESCs with reporter system expressed pluripotency markers and fluorescent signals produced by OCT4 reporter system. Also, they were capable of forming teratomas following subcutaneous injection into nude mice. Since reporter system enables the non-destructive classification of the condition of live pluripotent stem cells, this reporter cell line could be a useful resource for research on species-specific pluripotency. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1873-5061 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1873506121004566; https://doaj.org/toc/1873-5061 |
| DOI: |
10.1016/j.scr.2021.102609 |
| URL الوصول: |
https://doaj.org/article/f078c415f4b443b8bde8dcd85c315741 |
| رقم الانضمام: |
edsdoj.f078c415f4b443b8bde8dcd85c315741 |
| قاعدة البيانات: |
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