Academic Journal
New polychlorinated bibenzyls from Rhododendron minutiflorum
العنوان: | New polychlorinated bibenzyls from Rhododendron minutiflorum |
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المؤلفون: | Yang-Li Zhu, Li Deng, Yu Tang, Xian-Zhe Fan, Yang Han, Mei Pan, Li-Jun Zhang, Hai-Bing Liao |
المصدر: | Natural Products and Bioprospecting, Vol 13, Iss 1, Pp 1-9 (2023) |
بيانات النشر: | SpringerOpen, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Botany |
مصطلحات موضوعية: | Rhododendron minutiflorum, Polychlorinated bibenzyls, Matrine, Insecticidal activity, Diaphorina citri, α-Glucosidase inhibitory activity, Botany, QK1-989 |
الوصف: | Abstract Five new polychlorinated bibenzyls (1–5) along with 3 known compounds (6–8) were isolated from the stems and leaves of Rhododendron minutiflorum. The chemical structures of all the isolates were determined by spectroscopic methods, and compounds 1 and 2 were further verified by single-crystal X-ray diffraction analyses. Compounds 1–5 were halogenated compounds which bear three to five chlorine atoms in their chemical structures. Biologically, compounds 2, 5 and 6 showed varying degrees of toxicity toward the Asian citrus psyllid (Diaphorina citri) with LD50 values 27.15, 17.02 and 16.20 mg/L, respectively. These values were comparable to the positive control matrine (LD50 = 11.86 mg/L), which were calculated using observations on day 6. Meanwhile, compound 4 had α-glucosidase inhibitory activity with IC50 value of 17.87 ± 0.74 μM. Graphical Abstract |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2192-2195 2192-2209 |
Relation: | https://doaj.org/toc/2192-2195; https://doaj.org/toc/2192-2209 |
DOI: | 10.1007/s13659-022-00364-x |
URL الوصول: | https://doaj.org/article/f04dfd7c250943a9ac19272175d0d31c |
رقم الانضمام: | edsdoj.f04dfd7c250943a9ac19272175d0d31c |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 21922195 21922209 |
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DOI: | 10.1007/s13659-022-00364-x |