Asprosin in nonalcoholic fatty liver disease and hypothyroidism: a case-control study

التفاصيل البيبلوغرافية
العنوان:	Asprosin in nonalcoholic fatty liver disease and hypothyroidism: a case-control study
المؤلفون:	Mona Abdel-Latif Aboul-Seoud, Mohamed Kamal Ghitany, Ola Atef Sharaki, Ahmed Alaa Abdul-Aziz, Mohammed Said Sayed Shater
المصدر:	Alexandria Journal of Medicine, Vol 60, Iss 1, Pp 265-273 (2024)
بيانات النشر:	Taylor & Francis Group, 2024.
سنة النشر:	2024
المجموعة:	LCC:Medicine
مصطلحات موضوعية:	NAFLD, hypothyroidism, asprosin, insulin resistance, Medicine
الوصف:	Purpose The present study aimed to determine the serum level of asprosin, a novel glucogenic and orexigenic hormone, in NAFLD and hypothyroidism patients.Methods This is a case–control study that included three groups of age and sex-matched subjects: hypothyroid patients with NAFLD (n = 26), hypothyroid patients without NAFLD (n = 25) and normal control subjects (n = 27). A detailed clinical history was obtained, and an examination was performed. Laboratory tests included fasting plasma glucose and insulin, lipid profile, TSH, free T4, AST, ALT, albumin, and asprosin. The homeostatic model assessment of insulin resistance (HOMA-IR) score was calculated. Abdominal ultrasonography was performed to calculate the hepatorenal index and define participants with NAFLD. The data were statistically analyzed.Results There was a statistically significant difference between the three groups regarding serum asprosin concentration (p
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	20905068 2090-5076 2090-5068
Relation:	https://doaj.org/toc/2090-5068; https://doaj.org/toc/2090-5076
DOI:	10.1080/20905068.2024.2381153
URL الوصول:	https://doaj.org/article/bf5f905fd0bb4e0f894e0ca881163c43
رقم الانضمام:	edsdoj.bf5f905fd0bb4e0f894e0ca881163c43
قاعدة البيانات:	Directory of Open Access Journals

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الوصف
تدمد:	20905068 20905076
DOI:	10.1080/20905068.2024.2381153