التفاصيل البيبلوغرافية
العنوان: |
Impact of COVID-19 vaccination in patients with epilepsy |
المؤلفون: |
Haidy Elshebawy, Nirmeen A. Kishk, Nouran Alaa, Mona Hussein, Mohamed Abdelghaffar, Rehab Magdy |
المصدر: |
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, Vol 60, Iss 1, Pp 1-6 (2024) |
بيانات النشر: |
SpringerOpen, 2024. |
سنة النشر: |
2024 |
المجموعة: |
LCC:Neurosciences. Biological psychiatry. Neuropsychiatry |
مصطلحات موضوعية: |
People with epilepsy, COVID-19 vaccines, Seizure exacerbation, Vaccine safety, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
الوصف: |
Abstract Background The risk of seizure aggravation following coronavirus disease 2019 (COVID-19) vaccines is a major cause behind vaccine hesitancy among patients with epilepsy (PWE), resulting in lower immunization rates. This work aimed to investigate the impact of COVID-19 different vaccines on seizure control in PWE. Results This study was conducted on 110 PWE who received at least the first dose of any COVID-19 vaccine. Sixty-one (55.5%) patients did not develop any side effects from vaccination. There was no statistically significant change in seizure frequency following receiving COVID-19 vaccines, either adenoviral vector vaccines, inactivated vaccines, or mRNA vaccines (P = 0.733, 0.778, respectively). Twelve patients (10.9%) experienced seizure exacerbation following COVID-19 vaccination; seizure occurrence in the first 24 h immediately after the vaccine was reported in only one patient. There were no statistically significant differences between patients who developed seizure exacerbation following COVID-19 vaccination and those who did not develop regarding age, age at onset, seizure etiology, type of vaccine, or seizure exacerbation following COVID-19 infection. Conclusions There is a low likelihood of COVID-19 vaccine-related seizure exacerbations in PWE. This data can be utilized to counsel PWE regarding the safety of COVID-19 vaccination. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
1687-8329 |
Relation: |
https://doaj.org/toc/1687-8329 |
DOI: |
10.1186/s41983-024-00924-7 |
URL الوصول: |
https://doaj.org/article/bbc4238ab6f340e0a6f893d8f0c10dd1 |
رقم الانضمام: |
edsdoj.bbc4238ab6f340e0a6f893d8f0c10dd1 |
قاعدة البيانات: |
Directory of Open Access Journals |