Academic Journal

Impact of COVID-19 vaccination in patients with epilepsy

التفاصيل البيبلوغرافية
العنوان: Impact of COVID-19 vaccination in patients with epilepsy
المؤلفون: Haidy Elshebawy, Nirmeen A. Kishk, Nouran Alaa, Mona Hussein, Mohamed Abdelghaffar, Rehab Magdy
المصدر: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, Vol 60, Iss 1, Pp 1-6 (2024)
بيانات النشر: SpringerOpen, 2024.
سنة النشر: 2024
المجموعة: LCC:Neurosciences. Biological psychiatry. Neuropsychiatry
مصطلحات موضوعية: People with epilepsy, COVID-19 vaccines, Seizure exacerbation, Vaccine safety, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
الوصف: Abstract Background The risk of seizure aggravation following coronavirus disease 2019 (COVID-19) vaccines is a major cause behind vaccine hesitancy among patients with epilepsy (PWE), resulting in lower immunization rates. This work aimed to investigate the impact of COVID-19 different vaccines on seizure control in PWE. Results This study was conducted on 110 PWE who received at least the first dose of any COVID-19 vaccine. Sixty-one (55.5%) patients did not develop any side effects from vaccination. There was no statistically significant change in seizure frequency following receiving COVID-19 vaccines, either adenoviral vector vaccines, inactivated vaccines, or mRNA vaccines (P = 0.733, 0.778, respectively). Twelve patients (10.9%) experienced seizure exacerbation following COVID-19 vaccination; seizure occurrence in the first 24 h immediately after the vaccine was reported in only one patient. There were no statistically significant differences between patients who developed seizure exacerbation following COVID-19 vaccination and those who did not develop regarding age, age at onset, seizure etiology, type of vaccine, or seizure exacerbation following COVID-19 infection. Conclusions There is a low likelihood of COVID-19 vaccine-related seizure exacerbations in PWE. This data can be utilized to counsel PWE regarding the safety of COVID-19 vaccination.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1687-8329
Relation: https://doaj.org/toc/1687-8329
DOI: 10.1186/s41983-024-00924-7
URL الوصول: https://doaj.org/article/bbc4238ab6f340e0a6f893d8f0c10dd1
رقم الانضمام: edsdoj.bbc4238ab6f340e0a6f893d8f0c10dd1
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16878329
DOI:10.1186/s41983-024-00924-7