التفاصيل البيبلوغرافية
| العنوان: |
Synthesis and Antifungal Activity of the Derivatives of Novel Pyrazole Carboxamide and Isoxazolol Pyrazole Carboxylate |
| المؤلفون: |
Jialong Sun, Yuanming Zhou |
| المصدر: |
Molecules, Vol 20, Iss 3, Pp 4383-4394 (2015) |
| بيانات النشر: |
MDPI AG, 2015. |
| سنة النشر: |
2015 |
| المجموعة: |
LCC:Organic chemistry |
| مصطلحات موضوعية: |
pyrazole carboxamide, isoxazolol pyrazole carboxylate, antifungal activity, synthesis, fungi, Organic chemistry, QD241-441 |
| الوصف: |
A series of pyrazole carboxamide and isoxazolol pyrazole carboxylate derivatives were designed and synthesized in this study. The structures of the compounds were elucidated based on spectral data (infrared, proton nuclear magnetic resonance and mass spectroscopy). Then, all of the compounds were bioassayed in vitro against four types of phytopathogenic fungi (Alternaria porri, Marssonina coronaria, Cercospora petroselini and Rhizoctonia solani) using the mycelium growth inhibition method. The results showed that some of the synthesized pyrazole carboxamides displayed notable antifungal activity. The isoxazole pyrazole carboxylate 7ai exhibited significant antifungal activity against R. solani, with an EC50 value of 0.37 μg/mL. Nonetheless, this value was lower than that of the commercial fungicide, carbendazol. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1420-3049 |
| Relation: |
http://www.mdpi.com/1420-3049/20/3/4383; https://doaj.org/toc/1420-3049 |
| DOI: |
10.3390/molecules20034383 |
| URL الوصول: |
https://doaj.org/article/bb3da290cf5b4c629ed3fb0620fc1570 |
| رقم الانضمام: |
edsdoj.bb3da290cf5b4c629ed3fb0620fc1570 |
| قاعدة البيانات: |
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