Academic Journal
Local Brain Ischemia Inducing in Rat by Embolic Model of Stroke
| العنوان: | Local Brain Ischemia Inducing in Rat by Embolic Model of Stroke |
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| المؤلفون: | Mohammad Allahtavakoli, Rooholah Moloudi, Behnam Heshmatian, Mohammad Reza Rahmani, Mohammad Ebrahim Rezvani |
| المصدر: | مجله دانشکده پزشکی اصفهان, Vol 26, Iss 89 (2008) |
| بيانات النشر: | Isfahan University of Medical Sciences, 2008. |
| سنة النشر: | 2008 |
| المجموعة: | LCC:Medicine LCC:Medicine (General) |
| مصطلحات موضوعية: | Medicine, Medicine (General), R5-920 |
| الوصف: | Abstract In patients affected with stroke, most ischemic episodes (80-90%) occur due to occlusion of middle cerebral artery (MCA). Background: Some of blood through femoral artery was withdrawn into a PE- 50 catheter and kept for 2 h in room temperature and 22 h at 4°C to allow old clot formation. Then the catheter was advanced 17 mm in the internal carotid artery until its tip was 1 to 2 mm away from MCA origin. 3-5 µl the preformed clot or 5 µl saline (for sham- operated animals) were injected. Behavioral deficits and seizure activities were recorded at 2, 24, and 48 hours after clot injection. Then the rats were decapitated to remove the brains and prepare them for Tetrazoliume chloride (TTC) staining and analyzing. Methods: When 3 or 5 µl clots were injected, infarct volume was 29.35±1.26% and 16.15±94% respectively (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Persian |
| تدمد: | 1027-7595 1735-854X |
| Relation: | http://jims.mui.ac.ir/index.php/jims/article/view/126; https://doaj.org/toc/1027-7595; https://doaj.org/toc/1735-854X |
| URL الوصول: | https://doaj.org/article/baeeb90e4e064090beae2085af1d603b |
| رقم الانضمام: | edsdoj.baeeb90e4e064090beae2085af1d603b |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 10277595 1735854X |
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