Academic Journal

CRISPR/Cas tools for enhancing the biopreservation ability of lactic acid bacteria in aquatic products

التفاصيل البيبلوغرافية
العنوان: CRISPR/Cas tools for enhancing the biopreservation ability of lactic acid bacteria in aquatic products
المؤلفون: Huina Dong, Huiying Wang, Shaoping Fu, Dawei Zhang
المصدر: Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
بيانات النشر: Frontiers Media S.A., 2022.
سنة النشر: 2022
المجموعة: LCC:Biotechnology
مصطلحات موضوعية: lactic acid bacteria, aquatic products biopreservation, CRISPR/Cas system, genome editing, transcriptional regulation, Biotechnology, TP248.13-248.65
الوصف: Lactic acid bacteria (LAB) plays a crucial role in aquatic products biopreservation as it can inhibit many bacteria, in particular the specific spoilage organisms (SSOs) of aquatic products, by competing for nutrients or producing one or more metabolites which have antimicrobial activity, such as bacteriocins. Lactobacillus spp. and Lactococcus spp. are the most commonly used Lactic acid bacterias in aquatic products preservation. The improvement of gene editing tools is particularly important for developing new lactic acid bacteria strains with superior properties for aquatic products biopreservation. This review summarized the research progress of the most widely used CRISPR/Cas-based genome editing tools in Lactobacillus spp. and Lactococcus spp. The genome editing tools based on homologous recombination and base editor were described. Then, the research status of CRISPRi in transcriptional regulation was reviewed briefly. This review may provide a reference for the application of CRISPR/Cas-based genome editing tools to other lactic acid bacteria species.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2296-4185
Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2022.1114588/full; https://doaj.org/toc/2296-4185
DOI: 10.3389/fbioe.2022.1114588
URL الوصول: https://doaj.org/article/ba2b5c7c5c6b42879cb874fa65216e68
رقم الانضمام: edsdoj.ba2b5c7c5c6b42879cb874fa65216e68
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22964185
DOI:10.3389/fbioe.2022.1114588