Academic Journal
Estimation and Correlation of Clinical Significance of Lipoprotein (a) as a Risk Factor of Atherosclerotic Vascular Events in Elderly: A 1-year Cross-sectional Study in KLE’s Dr. Prabhakar Kore Hospital and Medical Research Centre, Belagavi
| العنوان: | Estimation and Correlation of Clinical Significance of Lipoprotein (a) as a Risk Factor of Atherosclerotic Vascular Events in Elderly: A 1-year Cross-sectional Study in KLE’s Dr. Prabhakar Kore Hospital and Medical Research Centre, Belagavi |
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| المؤلفون: | Yashoda Tushar Maladkar, Veerappa Annasaheb Kothiwale |
| المصدر: | Journal of the Scientific Society, Vol 51, Iss 4, Pp 559-565 (2024) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | cardiovascular atherosclerotic vascular event, lipid profile, lipoprotein (a), neurological atherosclerotic vascular event, Medicine |
| الوصف: | Introduction: Lipoprotein (a) (Lp(a)) was identified as a variant of low-density lipoprotein (LDL) 40 years ago. Lp(a) consists of one LDL particle containing apoB-100 and one molecule of a large, highly polymorphic glycoprotein known as apo (a). The study aimed to evaluate and correlate the clinical significance of Lp(a) as a risk factor for atherosclerotic vascular events in the elderly population. Materials and Methods: This cross-sectional study was conducted among patients admitted in a tertiary care hospital for for 1 year. One hundred and forty-two study participants included in the study were divided into two groups atherosclerotic vascular event group (2 subgroups: Cardiovascular atherosclerotic vascular event subgroup and neurological atherosclerotic vascular event subgroup) and no atherosclerotic vascular event group. Detailed history, examination, and parameters such as serum Lp(a), serum high-density lipoproteins, LDL, total cholesterol, triglycerides, glycated hemoglobin, and creatinine were tested. Results: Among 142 study participants in the study, majority of study participants were male (n = 96, 67.6%). The mean age was 71.63 years. High Lp(a) levels were noted in 51.41% of study participants. High Lp(a) levels were seen in 56% of study participants in the cardiovascular atherosclerotic vascular event subgroup, 43.33% of study participants in the neurological atherosclerotic vascular event subgroup and 51.61% in no atherosclerotic vascular event group. Conclusion: Our study concludes that Lp(a) may not be used to infer any clinical significance, nor may it have any role to play as a risk factor for atherosclerotic vascular events in the elderly (age >65 years). |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0974-5009 2278-7127 |
| Relation: | https://journals.lww.com/10.4103/jss.jss_183_24; https://doaj.org/toc/0974-5009; https://doaj.org/toc/2278-7127 |
| DOI: | 10.4103/jss.jss_183_24 |
| URL الوصول: | https://doaj.org/article/ba04283f47254325902826e1f850a971 |
| رقم الانضمام: | edsdoj.ba04283f47254325902826e1f850a971 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 09745009 22787127 |
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| DOI: | 10.4103/jss.jss_183_24 |