التفاصيل البيبلوغرافية
| العنوان: |
Whole-organ analysis of TGF-β-mediated remodelling of the tumour microenvironment by tissue clearing |
| المؤلفون: |
Shimpei I. Kubota, Kei Takahashi, Tomoyuki Mano, Katsuhiko Matsumoto, Takahiro Katsumata, Shoi Shi, Kazuki Tainaka, Hiroki R. Ueda, Shogo Ehata, Kohei Miyazono |
| المصدر: |
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021) |
| بيانات النشر: |
Nature Portfolio, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Biology (General) |
| مصطلحات موضوعية: |
Biology (General), QH301-705.5 |
| الوصف: |
Shimpei Kubota et al. describe a pipeline for quantitative whole-organ analysis that that combines tissue clearing, 3D imaging, and machine learning for analysis of the tumour microenvironment. The authors apply this in a mouse model of lung tumour and reveal the role of TGF-β in remodelling the cellular microenvironment favouring metastatic invasion. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2399-3642 |
| Relation: |
https://doaj.org/toc/2399-3642 |
| DOI: |
10.1038/s42003-021-01786-y |
| URL الوصول: |
https://doaj.org/article/b9b43d1be89a48cd9299b239e2a3ca11 |
| رقم الانضمام: |
edsdoj.b9b43d1be89a48cd9299b239e2a3ca11 |
| قاعدة البيانات: |
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