Academic Journal

IL-9 plays a critical role in helminth-induced protection against COVID-19-related cytokine storms

التفاصيل البيبلوغرافية
العنوان: IL-9 plays a critical role in helminth-induced protection against COVID-19-related cytokine storms
المؤلفون: ChunXiao Xiang, Gang Zhong, Huiqing Wang
المصدر: mBio, Vol 15, Iss 7 (2024)
بيانات النشر: American Society for Microbiology, 2024.
سنة النشر: 2024
المجموعة: LCC:Microbiology
مصطلحات موضوعية: IL-9, COVID-19, cytokine storms, Trichinella sprialis, Microbiology, QR1-502
الوصف: ABSTRACT A recent study published in mBio by Cao et al. demonstrated that the helminth Trichinella sprialis (Ts) alleviates COVID-19-related cytokine storms in an IL-9-dependent way (Z. Cao, J. Wang, X. Liu, Y. Liu, et al., mBio 15:e00905-24, 2024, https://doi.org/10.1128/mbio.00905-24). A cytokine storm is a severe immune response characterized by the overproduction of proinflammatory cytokines, such as TNF-α and IFN-γ, leading to tissue damage and mortality in COVID-19 patients. This study indicated that IL-9 is crucial in protecting against cytokine storm syndromes associated with SARS-CoV-2 infection and proposed that anti-inflammatory molecules from Ts excretory/secretory (TsES) products could be a novel source for treating such illnesses.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2150-7511
Relation: https://doaj.org/toc/2150-7511
DOI: 10.1128/mbio.01229-24
URL الوصول: https://doaj.org/article/b9501278653a4c9eb3b31860864cc2e3
رقم الانضمام: edsdoj.b9501278653a4c9eb3b31860864cc2e3
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:21507511
DOI:10.1128/mbio.01229-24