Academic Journal

Early detection of sepsis using machine learning algorithms: a systematic review and network meta-analysis

التفاصيل البيبلوغرافية
العنوان: Early detection of sepsis using machine learning algorithms: a systematic review and network meta-analysis
المؤلفون: Mikhail Ya Yadgarov, Giovanni Landoni, Levan B. Berikashvili, Petr A. Polyakov, Kristina K. Kadantseva, Anastasia V. Smirnova, Ivan V. Kuznetsov, Maria M. Shemetova, Alexey A. Yakovlev, Valery V. Likhvantsev
المصدر: Frontiers in Medicine, Vol 11 (2024)
بيانات النشر: Frontiers Media S.A., 2024.
سنة النشر: 2024
المجموعة: LCC:Medicine (General)
مصطلحات موضوعية: sepsis, machine learning, network meta-analysis, decision trees, neural networks, Medicine (General), R5-920
الوصف: BackgroundWith machine learning (ML) carving a niche in diverse medical disciplines, its role in sepsis prediction, a condition where the ‘golden hour’ is critical, is of paramount interest. This study assesses the factors influencing the efficacy of ML models in sepsis prediction, aiming to optimize their use in clinical practice.MethodsWe searched Medline, PubMed, Google Scholar, and CENTRAL for studies published from inception to October 2023. We focused on studies predicting sepsis in real-time settings in adult patients in any hospital settings without language limits. The primary outcome was area under the curve (AUC) of the receiver operating characteristic. This meta-analysis was conducted according to PRISMA-NMA guidelines and Cochrane Handbook recommendations. A Network Meta-Analysis using the CINeMA approach compared ML models against traditional scoring systems, with meta-regression identifying factors affecting model quality.ResultsFrom 3,953 studies, 73 articles encompassing 457,932 septic patients and 256 models were analyzed. The pooled AUC for ML models was 0.825 and it significantly outperformed traditional scoring systems. Neural Network and Decision Tree models demonstrated the highest AUC metrics. Significant factors influencing AUC included ML model type, dataset type, and prediction window.ConclusionThis study establishes the superiority of ML models, especially Neural Network and Decision Tree types, in sepsis prediction. It highlights the importance of model type and dataset characteristics for prediction accuracy, emphasizing the necessity for standardized reporting and validation in ML healthcare applications. These findings call for broader clinical implementation to evaluate the effectiveness of these models in diverse patient groups.Systematic review registrationhttps://inplasy.com/inplasy-2023-12-0062/, identifier, INPLASY2023120062.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2296-858X
Relation: https://www.frontiersin.org/articles/10.3389/fmed.2024.1491358/full; https://doaj.org/toc/2296-858X
DOI: 10.3389/fmed.2024.1491358
URL الوصول: https://doaj.org/article/b916acce83b64b18b8aa3eba2dd13cca
رقم الانضمام: edsdoj.b916acce83b64b18b8aa3eba2dd13cca
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:2296858X
DOI:10.3389/fmed.2024.1491358