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Synergistic vesicle-vector systems for targeted delivery

التفاصيل البيبلوغرافية
العنوان: Synergistic vesicle-vector systems for targeted delivery
المؤلفون: Christine Ardelle Marquez, Cho-Im Oh, Gna Ahn, Woo-Ri Shin, Yang-Hoon Kim, Ji-Young Ahn
المصدر: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-25 (2024)
بيانات النشر: BMC, 2024.
سنة النشر: 2024
المجموعة: LCC:Biotechnology
LCC:Medical technology
مصطلحات موضوعية: Vesicle-vector system (VVS), Targeted delivery, Drug delivery system (DDS), Extracellular vesicle (EV), Liposome, Exosome, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5
الوصف: Abstract With the immense progress in drug delivery systems (DDS) and the rise of nanotechnology, challenges such as target specificity remain. The vesicle-vector system (VVS) is a delivery system that uses lipid-based vesicles as vectors for a targeted drug delivery. When modified with target-probing materials, these vesicles become powerful vectors for drug delivery with high target specificity. In this review, we discuss three general types of VVS based on different modification strategies: (1) vesicle-probes; (2) vesicle-vesicles; and (3) genetically engineered vesicles. The synthesis of each VVS type and their corresponding properties that are advantageous for targeted drug delivery, are also highlighted. The applications, challenges, and limitations of VVS are briefly examined. Finally, we share a number of insights and perspectives regarding the future of VVS as a targeted drug delivery system at the nanoscale. Graphical Abstract
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1477-3155
Relation: https://doaj.org/toc/1477-3155
DOI: 10.1186/s12951-023-02275-6
URL الوصول: https://doaj.org/article/b841e99ebdcd40e7a72843914bfe0fc2
رقم الانضمام: edsdoj.b841e99ebdcd40e7a72843914bfe0fc2
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14773155
DOI:10.1186/s12951-023-02275-6