Academic Journal
Insights into the neuroprotective properties of Biochanin-A
| العنوان: | Insights into the neuroprotective properties of Biochanin-A |
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| المؤلفون: | Sarah Hussein, Mai Fathy Tolba, Haidy E Michel, Samar Azab |
| المصدر: | Archives of Pharmaceutical Sciences Ain Shams University, Vol 6, Iss 2, Pp 181-195 (2022) |
| بيانات النشر: | Ain Shams University, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Therapeutics. Pharmacology |
| مصطلحات موضوعية: | biochanin a, neuroprotective, neurological disorder, antioxidant, anti-inflammatory, alzheimer’s, parkinson’s diseases, glioblastoma, Therapeutics. Pharmacology, RM1-950 |
| الوصف: | The global morbidity and mortality caused by neurological disorders are significant. Neurodegenerative disorders are anticipated to rise as the population ages because they typically manifest in mid-to-late life. The World Health Organization predicts that by 2050, two billion individuals would be 60 or older. So an emerging need for neuroprotective agents derived from natural sources with high efficacy and high safety profile. one of these natural agents is biochanin A, an isoflavone belonging to phytoestrogens, mainly found in red clover, soy, and chickpea, commercially available as a tablet, and has a wide range of pharmacological effects, such as antioxidant, anti-inflammatory, anti-apoptotic, antimicrobial, Estrogen-like, glucose and lipid metabolism modulatory, anti-cancer, and neuroprotective effects. Biochanin A was proven to be effective in multiple neurological diseases such as Alzheimer’s and Parkinson’s diseases, multiple sclerosis, stroke, brain injury, depression, anxiety, and glioblastoma. This review concentrates on the possible molecular mechanisms responsible for the neuroprotective effects of biochanin A in various neurological disorders. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2356-8380 2356-8399 |
| Relation: | https://aps.journals.ekb.eg/article_266860.html; https://doaj.org/toc/2356-8380; https://doaj.org/toc/2356-8399 |
| DOI: | 10.21608/APS.2022.154272.1097 |
| URL الوصول: | https://doaj.org/article/b7db9b8c773842e09ebe702f195d810e |
| رقم الانضمام: | edsdoj.b7db9b8c773842e09ebe702f195d810e |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 23568380 23568399 |
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| DOI: | 10.21608/APS.2022.154272.1097 |