Academic Journal

The association between Matrix Metallo-proteinases-9 (MMP-9) gene family polymorphisms and risk of Coronary Artery Disease (CAD): a systematic review and meta-analysis

التفاصيل البيبلوغرافية
العنوان: The association between Matrix Metallo-proteinases-9 (MMP-9) gene family polymorphisms and risk of Coronary Artery Disease (CAD): a systematic review and meta-analysis
المؤلفون: Reza Hassanzadeh-Makoui, Bahman Razi, Saeed Aslani, Danyal Imani, Seyedeh Samaneh Tabaee
المصدر: BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-15 (2020)
بيانات النشر: BMC, 2020.
سنة النشر: 2020
المجموعة: LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: Coronary artery disease, Matrix metalloproteinases, Genetic polymorphism, Meta-analysis, Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Abstract Background We performed a systematic review and meta-analysis of the Matrix metalloproteinases (MMP)-9 (C1562T), MMP-9 (R279Q), MMP-9 (P574R) and MMP-9 (R668Q) polymorphisms and risk of Coronary Artery Disease (CAD). Methods After a systematic literature search, pooled odds ratio (OR) and their corresponding 95% confidence interval (CI) were used to evaluate the strength of the association. Results We identified 40 studies with 11,792 cases and 8280 controls for C1562T, 7 case-control studies with 5525 cases and 2497 controls for R279Q, 2 studies with 1272 cases and 785 controls for P574R, and 2 studies with 1272 cases and 785 controls for R668Q. MMP-9 (C1562T) polymorphism was associated with increased risk of CAD under dominant model (OR = 1.41, P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2261
Relation: http://link.springer.com/article/10.1186/s12872-020-01510-4; https://doaj.org/toc/1471-2261
DOI: 10.1186/s12872-020-01510-4
URL الوصول: https://doaj.org/article/eb70d553979d406aab0fcb307bdbb471
رقم الانضمام: edsdoj.b70d553979d406aab0fcb307bdbb471
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14712261
DOI:10.1186/s12872-020-01510-4