التفاصيل البيبلوغرافية
| العنوان: |
The incidence of male breast cancer in Klinefelter Syndrome and its proposed mechanisms |
| المؤلفون: |
Benjamin Cook, Sasha Nayar, Simon Filson, Tet Yap |
| المصدر: |
Breast, Vol 78, Iss , Pp 103827- (2024) |
| بيانات النشر: |
Elsevier, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: |
Klinefelter syndrome, Klinefelter's syndrome, Male breast cancer, Incidence, Mechanism, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: |
Introduction: Men with Klinefelter Syndrome (KS) have been previously reported to have an increased risk of Male Breast Cancer (MBC). This systematic review provides the latest information regarding the incidence of MBC in the KS population compared to the standard male population and identifies mechanisms by which MBC may develop in KS. Material and methods: Several databases were searched including PubMed/MEDLINE and EMBASE between October 2023 and March 2024. The review was conducted in accordance with the latest Preferred Reporting Items for Systematic Reviews and Meta-analyses-guidelines and was registered in PROSPERO (CRD42024551110). Overall, 332 papers were identified for screening. Standardised incidence ratios (SIRs) were calculated in comparison to national incidence figures. Additionally, a literature review was conducted looking at potential MBC mechanisms in KS. Results: Across Danish and British cohorts, incidence of MBC in KS was significantly higher than the general population: SIR 18.1 (95 % CI: 13.53 to 24.74), p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1532-3080 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S0960977624001589; https://doaj.org/toc/1532-3080 |
| DOI: |
10.1016/j.breast.2024.103827 |
| URL الوصول: |
https://doaj.org/article/b676da47e7444a5cbbc207e2a038dbdf |
| رقم الانضمام: |
edsdoj.b676da47e7444a5cbbc207e2a038dbdf |
| قاعدة البيانات: |
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