Academic Journal

Construction of a vascularized fascia-prosthesis compound model with axial pedicle for ear reconstruction surgery

التفاصيل البيبلوغرافية
العنوان: Construction of a vascularized fascia-prosthesis compound model with axial pedicle for ear reconstruction surgery
المؤلفون: Guanmin Li, Chen Lei, Xiuying Shan, Xuejun Ni, Guojie Chen, Meishui Wang, Ruonan Ke, Biao Wang
المصدر: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
بيانات النشر: Frontiers Media S.A., 2023.
سنة النشر: 2023
المجموعة: LCC:Biotechnology
مصطلحات موضوعية: ear reconstruction, vascularized tissue engineering chamber, pedicled fascial flap, ear prosthesis, abdominal superficial vessels, Biotechnology, TP248.13-248.65
الوصف: Background: To design a vascular pedicled fascia-prosthesis compound model that can be used for ear reconstruction surgery.Methods: A vascularized tissue engineering chamber model was constructed in New Zealand rabbits, and fresh tissues were obtained after 4 weeks. The histomorphology and vascularization of the newly born tissue compound were analyzed and evaluated by tissue staining and Micro-CT scanning.Results: The neoplastic fibrous tissue formed in the vascularized tissue engineering chamber with the introduction of abdominal superficial vessels, similar to normal fascia, was superior to the control group in terms of vascularization, vascular density, total vascular volume, and total vascular volume/total tissue volume.Conclusion:In vivo, introducing abdominal superficial vessels in the tissue engineering chamber prepped for ear prosthesis may form a well-vascularized pedicled fascia-prosthesis compound that can be used for ear reconstruction.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2296-4185
Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2023.1126269/full; https://doaj.org/toc/2296-4185
DOI: 10.3389/fbioe.2023.1126269
URL الوصول: https://doaj.org/article/b6485371f9e74f88bcf274c5a5d035a7
رقم الانضمام: edsdoj.b6485371f9e74f88bcf274c5a5d035a7
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22964185
DOI:10.3389/fbioe.2023.1126269