التفاصيل البيبلوغرافية
| العنوان: |
Liquid biopsy in gastric cancer: A snapshot of the current state of the art |
| المؤلفون: |
Jessica Gasparello, Carlotta Ceccon, Valentina Angerilli, Tatiane Comunello, Marianna Sabbadin, Felipe D'Almeida Costa, Antonio Antico, Claudio Luchini, Paola Parente, Francesca Bergamo, Sara Lonardi, Matteo Fassan |
| المصدر: |
The Journal of Liquid Biopsy, Vol 7, Iss , Pp 100288- (2025) |
| بيانات النشر: |
Elsevier, 2025. |
| سنة النشر: |
2025 |
| المجموعة: |
LCC:Medicine |
| مصطلحات موضوعية: |
Liquid biopsy, Gastric cancer, Circulating markers, ctDNA, CNAs, Medicine |
| الوصف: |
Circulating tumor DNA (ctDNA) is nowadays considered a robust source to search for druggable tumoral genetic alterations, and in some specific settings liquid biopsy (LB) is already part of the diagnostics scenario and it has successfully implemented in the everyday practice. Three strengths make LB an extraordinary tool: i) to represent the complex molecular mosaicism that characterizes spatially heterogeneous malignancies; ii) to monitor in real-time the tumoral molecular landscape (i.e. to depict the longitudinal/temporal tumor evolution); iii) to ensure molecular profiling even in those cases in which tissue sampling is not feasible or not adequate. This review provides a snapshot of the current state of the art concerning ctDNA assay utility in gastric cancer (GC), testing its robustness as marker and seeking to understand the reasons for the delay in its application in clinical practice. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2950-1954 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2950195425000049; https://doaj.org/toc/2950-1954 |
| DOI: |
10.1016/j.jlb.2025.100288 |
| URL الوصول: |
https://doaj.org/article/b60fee3311c94bdf82c3e81729a1fcba |
| رقم الانضمام: |
edsdoj.b60fee3311c94bdf82c3e81729a1fcba |
| قاعدة البيانات: |
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