Academic Journal

Effects of a Bacopa monnieri extract (Bacognize®) on stress, fatigue, quality of life and sleep in adults with self-reported poor sleep: A randomised, double-blind, placebo-controlled study

التفاصيل البيبلوغرافية
العنوان: Effects of a Bacopa monnieri extract (Bacognize®) on stress, fatigue, quality of life and sleep in adults with self-reported poor sleep: A randomised, double-blind, placebo-controlled study
المؤلفون: Adrian L. Lopresti, Stephen J Smith, Sinan Ali, Alexandra P. Metse, John Kalns, Peter D. Drummond
المصدر: Journal of Functional Foods, Vol 85, Iss , Pp 104671- (2021)
بيانات النشر: Elsevier, 2021.
سنة النشر: 2021
المجموعة: LCC:Nutrition. Foods and food supply
مصطلحات موضوعية: Bacopa monnieri, Sleep, Stress, Cortisol, Herbal, Clinical trial, Nutrition. Foods and food supply, TX341-641
الوصف: In this 28-day, randomised, double-blind, placebo-controlled trial, 100 adults with self-reported poor sleep received either a placebo or a standardised Bacopa monnieri extract (150 mg twice daily). Outcome measures included the Bergen Insomnia Scale (primary outcome measure), Functional Outcomes of Sleep Questionnaire, Pittsburgh Sleep Diary, Short Form-36 Health Survey, and the Depression, Anxiety, and Stress Scale. Changes in salivary concentrations of cortisol, dehydroepiandrosterone sulfate, immunoglobulin A (sIgA), α-amylase (sAA), C-reactive protein, melatonin, and the fatigue biomarker index were also assessed. Based on the Bergen Insomnia Scale, Bacopa monnieri did not improve sleep patterns more than the placebo; however, it was associated with greater improvements in emotional wellbeing, general health, and pain-related symptoms. Bacopa monnieri was also associated with greater reductions in sIgA and sAA compared to the placebo. Future clinical trials using varying doses, treatment periods, and objective outcome measures will be important to validate these findings.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1756-4646
Relation: http://www.sciencedirect.com/science/article/pii/S1756464621003200; https://doaj.org/toc/1756-4646
DOI: 10.1016/j.jff.2021.104671
URL الوصول: https://doaj.org/article/b5b3fb6fdd1f4fd894cca48fe4ca6cbc
رقم الانضمام: edsdoj.b5b3fb6fdd1f4fd894cca48fe4ca6cbc
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17564646
DOI:10.1016/j.jff.2021.104671