التفاصيل البيبلوغرافية
العنوان: |
Effects of a Bacopa monnieri extract (Bacognize®) on stress, fatigue, quality of life and sleep in adults with self-reported poor sleep: A randomised, double-blind, placebo-controlled study |
المؤلفون: |
Adrian L. Lopresti, Stephen J Smith, Sinan Ali, Alexandra P. Metse, John Kalns, Peter D. Drummond |
المصدر: |
Journal of Functional Foods, Vol 85, Iss , Pp 104671- (2021) |
بيانات النشر: |
Elsevier, 2021. |
سنة النشر: |
2021 |
المجموعة: |
LCC:Nutrition. Foods and food supply |
مصطلحات موضوعية: |
Bacopa monnieri, Sleep, Stress, Cortisol, Herbal, Clinical trial, Nutrition. Foods and food supply, TX341-641 |
الوصف: |
In this 28-day, randomised, double-blind, placebo-controlled trial, 100 adults with self-reported poor sleep received either a placebo or a standardised Bacopa monnieri extract (150 mg twice daily). Outcome measures included the Bergen Insomnia Scale (primary outcome measure), Functional Outcomes of Sleep Questionnaire, Pittsburgh Sleep Diary, Short Form-36 Health Survey, and the Depression, Anxiety, and Stress Scale. Changes in salivary concentrations of cortisol, dehydroepiandrosterone sulfate, immunoglobulin A (sIgA), α-amylase (sAA), C-reactive protein, melatonin, and the fatigue biomarker index were also assessed. Based on the Bergen Insomnia Scale, Bacopa monnieri did not improve sleep patterns more than the placebo; however, it was associated with greater improvements in emotional wellbeing, general health, and pain-related symptoms. Bacopa monnieri was also associated with greater reductions in sIgA and sAA compared to the placebo. Future clinical trials using varying doses, treatment periods, and objective outcome measures will be important to validate these findings. |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
1756-4646 |
Relation: |
http://www.sciencedirect.com/science/article/pii/S1756464621003200; https://doaj.org/toc/1756-4646 |
DOI: |
10.1016/j.jff.2021.104671 |
URL الوصول: |
https://doaj.org/article/b5b3fb6fdd1f4fd894cca48fe4ca6cbc |
رقم الانضمام: |
edsdoj.b5b3fb6fdd1f4fd894cca48fe4ca6cbc |
قاعدة البيانات: |
Directory of Open Access Journals |