Academic Journal

Association between frailty, cerebral oxygenation and adverse post-operative outcomes in elderly patients undergoing non-cardiac surgery: An observational pilot study

التفاصيل البيبلوغرافية
العنوان: Association between frailty, cerebral oxygenation and adverse post-operative outcomes in elderly patients undergoing non-cardiac surgery: An observational pilot study
المؤلفون: Shariq Ali Khan, Henry Wenjie Chua, Premila Hirubalan, Ranjith Baskar Karthekeyan, Harikrishnan Kothandan
المصدر: Indian Journal of Anaesthesia, Vol 60, Iss 2, Pp 102-107 (2016)
بيانات النشر: Wolters Kluwer Medknow Publications, 2016.
سنة النشر: 2016
المجموعة: LCC:Anesthesiology
مصطلحات موضوعية: Cerebral oxygenation, frailty, non-cardiac surgery, post-operative outcome, Anesthesiology, RD78.3-87.3
الوصف: Background and Aims: Although both frailty and low cerebral oxygen saturation increase the risk of post-operative complications, their relationship is yet to be investigated. The purpose of this observational study was to investigate the association between frailty, intraoperative cerebral oxygen saturation and post-operative complications in elderly patients undergoing non-cardiac surgery. Methods: After approval from the Institutional Review Board, 25 elderly patients (>65 years) undergoing non-cardiac major surgery were included in this study. Pre-operatively, all included patients were assessed for frailty and classified into frail and non-frail groups. All patients had routine intraoperative monitors, and a cerebral oximeter applied during anaesthesia. The 'intraoperative' anaesthesiologist and the post-operative study investigator were blinded to cerebral oximeter readings throughout the study. The incidence of significant intraoperative cerebral oxygen desaturation, adverse post-operative outcomes and length of hospital stay were compared. Statistical significance was defined as a value of P < 0.05. Results: We found that the frail group had more intraoperative cerebral desaturation (odds ratio [OR] [95% confidence interval [CI]]: 1.75 [1.11–2.75]) and longer median (interquartile range) length of hospital stay compared to the non-frail group (13.5 days [8.75–27.5] and 8 days [6–11], respectively). Furthermore, in patients with a low-baseline cerebral oxygen saturation (
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0019-5049
Relation: http://www.ijaweb.org/article.asp?issn=0019-5049;year=2016;volume=60;issue=2;spage=102;epage=107;aulast=Khan; https://doaj.org/toc/0019-5049
DOI: 10.4103/0019-5049.176278
URL الوصول: https://doaj.org/article/b5a27b9352854a42912c9a0a1e706f6c
رقم الانضمام: edsdoj.b5a27b9352854a42912c9a0a1e706f6c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:00195049
DOI:10.4103/0019-5049.176278