Academic Journal
Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin – a case series
العنوان: | Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin – a case series |
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المؤلفون: | Femin Prasad, Riddhita De, Vittal Korann, Araba F. Chintoh, Gary Remington, Bjørn H. Ebdrup, Dan Siskind, Filip Krag Knop, Tina Vilsbøll, Anders Fink-Jensen, Margaret K. Hahn, Sri Mahavir Agarwal |
المصدر: | Therapeutic Advances in Psychopharmacology, Vol 13 (2023) |
بيانات النشر: | SAGE Publishing, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Therapeutics. Pharmacology LCC:Psychiatry |
مصطلحات موضوعية: | Therapeutics. Pharmacology, RM1-950, Psychiatry, RC435-571 |
الوصف: | Metformin is the currently accepted first-line treatment for antipsychotic-associated weight gain (AAWG). However, not all patients benefit from metformin. Glucagon-like peptide-1 receptor agonists (GLP1-RA) have shown promise in the management of obesity in the general population, with preliminary evidence supporting efficacy in AAWG. Semaglutide is a weekly injectable GLP-1RA which received recent approval for obesity management and noted superiority over other GLP-1RAs. This study explored the efficacy and tolerability of semaglutide in AAWG among individuals with severe mental illness. A retrospective chart review of patients treated with semaglutide in the Metabolic Clinic at the Center for Addiction and Mental Health (CAMH) between 2019 and 2021 was conducted. Patients failing a trial of metformin ( |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2045-1261 20451253 |
Relation: | https://doaj.org/toc/2045-1261 |
DOI: | 10.1177/20451253231165169 |
URL الوصول: | https://doaj.org/article/b4b4361472ba49fd9f375efebb40983d |
رقم الانضمام: | edsdoj.b4b4361472ba49fd9f375efebb40983d |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20451261 20451253 |
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DOI: | 10.1177/20451253231165169 |