Academic Journal
أعرض في EDS

Recent Advances in Electrophysiological Recording Platforms for Brain and Heart Organoids

التفاصيل البيبلوغرافية
العنوان: Recent Advances in Electrophysiological Recording Platforms for Brain and Heart Organoids
المؤلفون: Won Gi Chung, Enji Kim, Hayoung Song, Jakyoung Lee, Sanghoon Lee, Kyeonghee Lim, Inhea Jeong, Jang-Ung Park
المصدر: Advanced NanoBiomed Research, Vol 2, Iss 12, Pp n/a-n/a (2022)
بيانات النشر: Wiley-VCH, 2022.
سنة النشر: 2022
المجموعة: LCC:Biotechnology
LCC:Medical technology
مصطلحات موضوعية: bioelectronics, electrophysiological recordings, multielectrode arrays, organoids, soft electronics, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5
الوصف: Organoids refer to 3D stem cells that have been developed to model neurological disorders in vitro. Typically, brain and heart organoids have gained interest for their potential to truly mimic the functional ability of real organs. Morphological analysis methods using immunostaining and slicing of the organoids are explored extensively over the past decade to evaluate the structures and functions of organoids. However, the destructiveness of these methods limits real‐time monitoring of the dynamic responses of the organoids. Therefore, electrophysiological functional analysis of organoids with minimally invasive forms can be a key solution to an improved understanding of the nature of complex organoids. Herein, the latest advances in the recording platforms are reviewed and a comprehensive study of considerations regarding electrophysiological factors is provided. Furthermore, current challenges are discussed along with prospects for next‐generation electrophysiological analysis of brain and heart organoids.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2699-9307
Relation: https://doaj.org/toc/2699-9307
DOI: 10.1002/anbr.202200081
URL الوصول: https://doaj.org/article/b44eedc83f644eb0a0d135e1ae5b3662
رقم الانضمام: edsdoj.b44eedc83f644eb0a0d135e1ae5b3662
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:26999307
DOI:10.1002/anbr.202200081