Academic Journal
Prognostic value of late gadolinium enhancement in cardiac MRI of non-ischemic dilated cardiomyopathy patients
| العنوان: | Prognostic value of late gadolinium enhancement in cardiac MRI of non-ischemic dilated cardiomyopathy patients |
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| المؤلفون: | Dibya Ranjan Behera, Ajit Kumar V K, Narayanan Namboodiri K K, Sivasankaran S, Krishna Kumar Mohanan Nair, Sanjay G, Kapilamoorthy T R, Arun Gopalakrishnan, Harikrishnan S |
| المصدر: | Indian Heart Journal, Vol 72, Iss 5, Pp 362-368 (2020) |
| بيانات النشر: | Elsevier, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Surgery LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: | Non-ischemic dilated cardiomyopathy, Late gadolinium enhancement, Heart failure, Sudden cardiac death, Surgery, RD1-811, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Background: The role of late gadolinium enhancement (LGE) in cardiac MRI (CMR) as prognostic marker in non-ischemic dilated cardiomyopathy (NIDCM) is evolving. Objective: To study the effect of LGE in the prognosis of NIDCM patients. Methods: 112 consecutive NIDCM patients, who underwent CMR, were prospectively followed up for 745 ± 320 days. Primary end point was occurrence of MACE {composite of all-cause mortality, resuscitated cardiac arrest, sustained ventricular tachycardia (VT)/appropriate ICD shock, heart failure (HF) hospitalization}. Results: LGE was present in 44 out of 112 patients (39%). The primary end point (MACE) was significantly higher in LGE + ve group compared to the LGE –ve group (72.7% vs. 29.4%; p 14% of LV predicted MACE with 90.6% sensitivity and 86% specificity. HR of LGE extent >14% of LV for MACE is 6.12; p 14% of LV volume were strongest predictor of MACE. Conclusion: LGE and its extent >14% predicts adverse cardiac events in NIDCM irrespective of LVEF and LGE location, pattern or distribution. This study emphasises the role of CMR in risk stratification of NIDCM patients and guiding therapy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0019-4832 |
| Relation: | http://www.sciencedirect.com/science/article/pii/S0019483220301395; https://doaj.org/toc/0019-4832 |
| DOI: | 10.1016/j.ihj.2020.06.011 |
| URL الوصول: | https://doaj.org/article/b4359a80045e4ed9b4c4647fac95a6b5 |
| رقم الانضمام: | edsdoj.b4359a80045e4ed9b4c4647fac95a6b5 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 00194832 |
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| DOI: | 10.1016/j.ihj.2020.06.011 |