Academic Journal
Effect of Topical Clove (Syzygium aromaticum (L.) Merr. & L.M.Perry) Gel on Premature Ejaculation: A Pilot Randomized Double-Blind Placebo-Controlled Clinical Trial
| العنوان: | Effect of Topical Clove (Syzygium aromaticum (L.) Merr. & L.M.Perry) Gel on Premature Ejaculation: A Pilot Randomized Double-Blind Placebo-Controlled Clinical Trial |
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| المؤلفون: | Ahmad Reza Sharifi Olounabadi, Fereidoun Khayyamfar, Mohammad Kamalinejad, Mahmood Salesi, Fatemeh Alijaniha, Fatemeh Emadi, Farzaneh Ghaffari, Babak Daneshfard, Mohsen Naseri |
| المصدر: | Traditional and Integrative Medicine, Vol 6, Iss 3 (2021) |
| بيانات النشر: | Tehran University of Medical Sciences, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Clove, Eugenia caryophyllata Thunb, Integrative medicine, Premature ejaculation, Persian medicine, Randomized controlled trial, Public aspects of medicine, RA1-1270 |
| الوصف: | Premature ejaculation is one of the most common sexual disorders worldwide without a satisfying treatment. In this study, we investigated the efficacy of a topical formulation of clove oil in premature ejaculation patients. Eligible patients were randomly divided into two groups to use either Syzygium aromaticum (SA) 1% gel or placebo gel 10 minutes before the intercourse for a period of 8 weeks. Outcome measurement were Premature Ejaculation Diagnostic Tool (PEDT) and International Index of Erectile Function (IIEF) questionnaires in addition to Intravaginal Ejaculation Latency Time (IELT). A total number of 22 (11 patients in each group) participants completed the study. At the end of the intervention, the IELT scores changed from 29.84 ± 18.59 to 97.09 ± 91.86 and 42.51 ± 13.98 to 52.45 ± 32.7 seconds in SA gel and placebo groups, respectively (p-value = 0.003). Also, the changes of PEDT scores in the SA gel group (from 14 ± 3.55 to 9.2 ± 4.56) comparing to that of placebo gel group (from 14.63 ± 3.61 to 13.5 ± 3.78) was significantly different (p-value =0.001). Moreover, results of IIEF questionnaire revealed significant improvement of “Intercourse Satisfaction” in SA gel group (p-value = 0.016). No adverse event was observed. It seems that SA gel could be beneficial in the treatment of premature ejaculation; however, it should be further evaluated in larger studies. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2476-5104 2476-5112 |
| Relation: | https://jtim.tums.ac.ir/index.php/jtim/article/view/382; https://doaj.org/toc/2476-5104; https://doaj.org/toc/2476-5112 |
| DOI: | 10.18502/tim.v6i3.7312 |
| URL الوصول: | https://doaj.org/article/cb3f166b8c5f4c799ee58f434d786ab4 |
| رقم الانضمام: | edsdoj.b3f166b8c5f4c799ee58f434d786ab4 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 24765104 24765112 |
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| DOI: | 10.18502/tim.v6i3.7312 |