Academic Journal

Gender inequalities in prescribing and initiation patterns of guideline-recommended drugs after acute myocardial infarction

التفاصيل البيبلوغرافية
العنوان: Gender inequalities in prescribing and initiation patterns of guideline-recommended drugs after acute myocardial infarction
المؤلفون: Irene López-Ferreruela, Sara Malo, Blanca Obón-Azuara, María José Rabanaque, Adriana Gamba, Sara Castel-Feced, Isabel Aguilar-Palacio
المصدر: BMC Public Health, Vol 25, Iss 1, Pp 1-12 (2025)
بيانات النشر: BMC, 2025.
سنة النشر: 2025
المجموعة: LCC:Public aspects of medicine
مصطلحات موضوعية: Myocardial infarction, Drugs prescription, Medication adherence, Secondary prevention, Gender inequalities, Real-world data, Public aspects of medicine, RA1-1270
الوصف: Abstract Background European guidelines recommend the prescription of certain drugs after acute myocardial infarction (AMI). The existence of gender differences in pharmacological treatment after an AMI has been described. This study aims to describe and analyse, using real-world data (RWD), whether there are gender differences in the prescribing patterns and initiation of treatment in secondary prevention after a first AMI, and which are the factors that explain these differences. Methods A population-based observational study of RWD was conducted in the CARhES (CArdiovascular Risk factors for hEalth Services research) cohort. The study included subjects who had experienced a first episode of AMI between 2017 and 2022, had survived the event, and had a minimum follow-up of 180 days. Results 3,975 subjects were followed 180 days after a first AMI. Women (27.8% of the study population) were older and had more comorbidities. Of the main guideline-recommended drugs, antiplatelets, lipid modifying agents and beta-blockers, were prescribed less often in women. Comedications such as rivaroxaban and calcium channel blockers were more likely to be prescribed in women. The proportion of subjects initiating treatment was similar in both genders. Overall, age and morbidity burden were the main contributors to differences in the prescribing patterns. Living in an urban area seemed to be a protective or mitigating factor. There were controversial results regarding socioeconomic level. Conclusion In our study population, women are older, have greater comorbidities and lower socioeconomic status. Despite this, gender inequalities in the prescribing patterns after a first AMI remains, as women appear to experience less therapeutic effort. It is crucial to analyse them from an intersectional perspective, considering the influence of multiple axes of inequality on health, in order to develop gender-sensitive strategies with a multidisciplinary approach.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2458
Relation: https://doaj.org/toc/1471-2458
DOI: 10.1186/s12889-025-21396-1
URL الوصول: https://doaj.org/article/b3e41cc280eb4053ac7484ceecbb67ed
رقم الانضمام: edsdoj.b3e41cc280eb4053ac7484ceecbb67ed
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14712458
DOI:10.1186/s12889-025-21396-1