التفاصيل البيبلوغرافية
| العنوان: |
How to Feed the Mammalian Gut Microbiota: Bacterial and Metabolic Modulation by Dietary Fibers |
| المؤلفون: |
Chiara Ferrario, Rosario Statello, Luca Carnevali, Leonardo Mancabelli, Christian Milani, Marta Mangifesta, Sabrina Duranti, Gabriele A. Lugli, Beatriz Jimenez, Samantha Lodge, Alice Viappiani, Giulia Alessandri, Margerita Dall’Asta, Daniele Del Rio, Andrea Sgoifo, Douwe van Sinderen, Marco Ventura, Francesca Turroni |
| المصدر: |
Frontiers in Microbiology, Vol 8 (2017) |
| بيانات النشر: |
Frontiers Media S.A., 2017. |
| سنة النشر: |
2017 |
| المجموعة: |
LCC:Microbiology |
| مصطلحات موضوعية: |
diet, microbiota, dietary fibers, rat model, acetate, succinate, Microbiology, QR1-502 |
| الوصف: |
The composition of the gut microbiota of mammals is greatly influenced by diet. Therefore, evaluation of different food ingredients that may promote changes in the gut microbiota composition is an attractive approach to treat microbiota disturbances. In this study, three dietary fibers, such as inulin (I, 10%), resistant starch (RS, 10%), and citrus pectin (3%), were employed as supplements to normal chow diet of adult male rats for 2 weeks. Fecal microbiota composition and corresponding metabolite profiles were assessed before and after prebiotics supplementation. A general increase in the Bacteroidetes phylum was detected with a concurrent reduction in Firmicutes, in particular for I and RS experiments, while additional changes in the microbiota composition were evident at lower taxonomic levels for all the three substrates. Such modifications in the microbiota composition were correlated with changes in metabolic profiles of animals, in particular changes in acetate and succinate levels. This study represents a first attempt to modulate selectively the abundance and/or metabolic activity of various members of the gut microbiota by means of dietary fiber. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1664-302X |
| Relation: |
http://journal.frontiersin.org/article/10.3389/fmicb.2017.01749/full; https://doaj.org/toc/1664-302X |
| DOI: |
10.3389/fmicb.2017.01749 |
| URL الوصول: |
https://doaj.org/article/cb3afa82de184300b409016d78453a56 |
| رقم الانضمام: |
edsdoj.b3afa82de184300b409016d78453a56 |
| قاعدة البيانات: |
Directory of Open Access Journals |
Full Text Finder