التفاصيل البيبلوغرافية
| العنوان: |
High Na+ Salt Diet and Remodeling of Vascular Smooth Muscle and Endothelial Cells |
| المؤلفون: |
Ghassan Bkaily, Yanick Simon, Ashley Jazzar, Houssein Najibeddine, Alexandre Normand, Danielle Jacques |
| المصدر: |
Biomedicines, Vol 9, Iss 8, p 883 (2021) |
| بيانات النشر: |
MDPI AG, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Biology (General) |
| مصطلحات موضوعية: |
Na+ salt, hypertension, Na+ salt sensitive hypertension, vascular endothelial cells, vascular smooth muscle cells, glycocalyx, Biology (General), QH301-705.5 |
| الوصف: |
Our knowledge on essential hypertension is vast, and its treatment is well known. Not all hypertensives are salt-sensitive. The available evidence suggests that even normotensive individuals are at high cardiovascular risk and lower survival rate, as blood pressure eventually rises later in life with a high salt diet. In addition, little is known about high sodium (Na+) salt diet-sensitive hypertension. There is no doubt that direct and indirect Na+ transporters, such as the Na/Ca exchanger and the Na/H exchanger, and the Na/K pump could be implicated in the development of high salt-induced hypertension in humans. These mechanisms could be involved following the destruction of the cell membrane glycocalyx and changes in vascular endothelial and smooth muscle cells membranes’ permeability and osmolarity. Thus, it is vital to determine the membrane and intracellular mechanisms implicated in this type of hypertension and its treatment. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2227-9059 |
| Relation: |
https://www.mdpi.com/2227-9059/9/8/883; https://doaj.org/toc/2227-9059 |
| DOI: |
10.3390/biomedicines9080883 |
| URL الوصول: |
https://doaj.org/article/b2d6023b52ed417880e1172ae1d2c5a6 |
| رقم الانضمام: |
edsdoj.b2d6023b52ed417880e1172ae1d2c5a6 |
| قاعدة البيانات: |
Directory of Open Access Journals |
Full Text Finder