التفاصيل البيبلوغرافية
| العنوان: |
Validity of the Systemic Lupus Erythematosus Disease Activity 2000-Glucocorticoid Index, its association with the Physician Global Assessment, and potential association with disease damage |
| المؤلفون: |
Basma M. Medhat, Lobna A. Maged, Doaa A. Teleb, Sally S. Mohamed, Angie Y. Afifi, Dina M. T. Koptan, Walaa Abdelrahman, Dalia Dorgham, Eman Hany Elsebaie, Naglaa Afifi, Sahar A. Ahmed, Mervat E. Behairy, Hala Ramadan |
| المصدر: |
The Egyptian Journal of Internal Medicine, Vol 37, Iss 1, Pp 1-7 (2025) |
| بيانات النشر: |
SpringerOpen, 2025. |
| سنة النشر: |
2025 |
| المجموعة: |
LCC:Internal medicine |
| مصطلحات موضوعية: |
Systemic lupus erythematosus, SLEDAI-2 K, Glucocorticoid, Physician Global Assessment, Disease Activity, Disease Damage, Internal medicine, RC31-1245 |
| الوصف: |
Abstract Background The Systemic Lupus Erythematosus Disease Activity-2000 Glucocorticoid Index (SLEDAI-2 KG) accounts for glucocorticoids and possibly promising. The Physician Global Assessment (PGA) is subjective and debatable. Objectives Assessment of the validity of the SLEDAI-2 KG, its association with the PGA, and their potential association with the disease damage. Methods A cross-sectional study included SLE patients managed at 2 tertiary centers in Egypt were conducted. The SLEDAI-2 K was the gold standard score for assessment the disease activity. The SLEDAI-2 KG incorporates glucocorticoids’ dosage through an ordinal weight. The PGA (scale: 0–3) was categorized according to the PGA international standardization consensus in SLE study (PISCOS). Results The study included 608 patients [546 (89.8%) females and [62 (10.2%) males; age at onset: 27.5 ± 8.5 years; age at assessment: 31.4 ± 9.4 years; disease duration: 6.1 ± 5.5 years for females]. The mean SLEDAI-2 K, SLEDAI-2 KG, and PGA was 11.9 ± 9.3, 16 ± 10.5, and 1.2 ± 0.8, respectively. The correlation between both the SLEDAI-2 KG (r: 0.96, p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2090-9098 |
| Relation: |
https://doaj.org/toc/2090-9098 |
| DOI: |
10.1186/s43162-024-00389-3 |
| URL الوصول: |
https://doaj.org/article/ab205cb6d093485dab070e64fbd0cb86 |
| رقم الانضمام: |
edsdoj.b205cb6d093485dab070e64fbd0cb86 |
| قاعدة البيانات: |
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