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Insulin Resistance and Acne: The Role of Metformin as Alternative Therapy in Men

التفاصيل البيبلوغرافية
العنوان: Insulin Resistance and Acne: The Role of Metformin as Alternative Therapy in Men
المؤلفون: Aikaterini Andreadi, Saverio Muscoli, Rojin Tajmir, Marco Meloni, Alessandro Minasi, Carolina Muscoli, Sara Ilari, Vincenzo Mollace, David Della Morte, Alfonso Bellia, Elena Campione, Nicola Di Daniele, Davide Lauro
المصدر: Pharmaceuticals, Vol 16, Iss 1, p 27 (2022)
بيانات النشر: MDPI AG, 2022.
سنة النشر: 2022
المجموعة: LCC:Medicine
LCC:Pharmacy and materia medica
مصطلحات موضوعية: insulin resistance, metformin, acne, drug efficacy evaluation, Medicine, Pharmacy and materia medica, RS1-441
الوصف: The association between acne and insulin resistance has not been investigated as thoroughly in males as it has been in women, despite the fact that in adult men, acne prevalence has grown. On the face, sebaceous glands produce and secrete sebum, which lubricates the skin and protects it from friction. Metformin, an insulin-sensitizing medication, may modify the association between acne vulgaris and insulin resistance (IR). Individuals with IR, metabolic syndrome or with impaired glucose tolerance are sometimes treated ‘off label’ with Metformin. In these conditions, IR may be a leading factor in the pathogenesis of acne, and in men, Metformin treatment may reduce the Global Acne Grading System (GAGS) score by enhancing insulin sensitivity. However, additional clinical studies are required to corroborate these assumptions.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 16010027
1424-8247
Relation: https://www.mdpi.com/1424-8247/16/1/27; https://doaj.org/toc/1424-8247
DOI: 10.3390/ph16010027
URL الوصول: https://doaj.org/article/b1cb7537d3844a3ab84eeb34f9b0c4c7
رقم الانضمام: edsdoj.b1cb7537d3844a3ab84eeb34f9b0c4c7
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16010027
14248247
DOI:10.3390/ph16010027