Academic Journal

Outcomes of stroke patients undergoing thrombolysis in Sri Lanka; an observational prospective study from a low-middle income country

التفاصيل البيبلوغرافية
العنوان: Outcomes of stroke patients undergoing thrombolysis in Sri Lanka; an observational prospective study from a low-middle income country
المؤلفون: H. M. M. T. B. Herath, Chaturaka Rodrigo, A. M. B. D. Alahakoon, Sathyajith Buddhika Ambawatte, Sunethra Senanayake, Bimsara Senanayake, Arjuna Fernando
المصدر: BMC Neurology, Vol 21, Iss 1, Pp 1-9 (2021)
بيانات النشر: BMC, 2021.
سنة النشر: 2021
المجموعة: LCC:Neurology. Diseases of the nervous system
مصطلحات موضوعية: Stroke, Thrombolysis, Sri Lanka, Observational prospective study, Neurology. Diseases of the nervous system, RC346-429
الوصف: Abstract Background Stroke related deaths are relatively higher in low- and middle-income countries where only a fraction of eligible patients undergo thrombolysis. There is also limited evidence on post-thrombolysis outcomes of patients from Asian countries in these income bands. Methods This is a single center prospective observational study of a patient cohort with acute ischaemic stroke, undergoing thrombolysis with alteplase (low and standard dose), over a 24-month period in 2019/2020. Modified Rankin scale (mRS) for dependency at 3 months (primary outcome), duration of hospital stay, incidence of symptomatic intracranial haemorrhages and all-cause mortality at 3 months (secondary outcomes) were recorded. Demographic, clinical and treatment related factors associated with these outcomes were explored. Results Eighty-nine patients (males – 61, 69%, mean age: 60 years ±12.18) were recruited. Time from symptom onset to reperfusion was 174 min ± 56.50. Fifty-one patients were independent according to mRS, 11 (12.4%) patients died, and 11 (12.5%) developed symptomatic intracranial haemorrhages by 3 months. Functional independence at 3 months was independently associated with National Institutes of Health Stroke Scale (NIHSS) on admission (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1471-2377
Relation: https://doaj.org/toc/1471-2377
DOI: 10.1186/s12883-021-02475-3
URL الوصول: https://doaj.org/article/b1289c10e8ef4d2bb5c14a26c8e81625
رقم الانضمام: edsdoj.b1289c10e8ef4d2bb5c14a26c8e81625
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14712377
DOI:10.1186/s12883-021-02475-3