Academic Journal

Clinical characteristics and outcome of IgG4-related disease with hypocomplementemia: a prospective cohort study

التفاصيل البيبلوغرافية
العنوان: Clinical characteristics and outcome of IgG4-related disease with hypocomplementemia: a prospective cohort study
المؤلفون: Linyi Peng, Hui Lu, Jiaxin Zhou, Panpan Zhang, Jieqiong Li, Zheng Liu, Di Wu, Shangzhu Zhang, Yunjiao Yang, Wei Bai, Li Wang, Yunyun Fei, Wen Zhang, Yan Zhao, Xiaofeng Zeng, Fengchun Zhang
المصدر: Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-10 (2021)
بيانات النشر: BMC, 2021.
سنة النشر: 2021
المجموعة: LCC:Diseases of the musculoskeletal system
مصطلحات موضوعية: IgG4-related disease, Hypocomplementemia, Complement, Immunoglobulin G4, Relapse, Diseases of the musculoskeletal system, RC925-935
الوصف: Abstract Background Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized systemic, immune-mediated, and fibro-inflammatory disease. Hypocomplementemia was found in part of IgG4-RD patients especially in the setting of active disease. Objectives This study aimed to clarify the clinical features, treatment efficacy, and outcome in IgG4-RD patients with hypocomplementemia. Methods 312 IgG4-RD patients were recruited in our prospective cohort conducted in Peking Union Medical College Hospital. Patients were divided into hypocomplementemia group and normal complement group according to serum C3 and C4 levels measured at baseline before treatment. Low serum C3 levels (
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1478-6362
Relation: https://doaj.org/toc/1478-6362
DOI: 10.1186/s13075-021-02481-3
URL الوصول: https://doaj.org/article/b0c285cb03204a7681fe17a5caa29da7
رقم الانضمام: edsdoj.b0c285cb03204a7681fe17a5caa29da7
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:14786362
DOI:10.1186/s13075-021-02481-3