التفاصيل البيبلوغرافية
| العنوان: |
Lyl-1 regulates primitive macrophages and microglia development |
| المؤلفون: |
Shoutang Wang, Deshan Ren, Brahim Arkoun, Anna-Lila Kaushik, Gabriel Matherat, Yann Lécluse, Dominik Filipp, William Vainchenker, Hana Raslova, Isabelle Plo, Isabelle Godin |
| المصدر: |
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021) |
| بيانات النشر: |
Nature Portfolio, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Biology (General) |
| مصطلحات موضوعية: |
Biology (General), QH301-705.5 |
| الوصف: |
Wang et al. use transcriptomic analysis to show that disruption of the transcription factor Lyl-1 in primitive macrophage progenitors results in defective differentiation that impacts on embryonic patterning and neurodevelopment. They also show that Lyl-1 disruption leads to a reduction in mature microglia, thus revealing its role in macrophage and microglial development |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2399-3642 |
| Relation: |
https://doaj.org/toc/2399-3642 |
| DOI: |
10.1038/s42003-021-02886-5 |
| URL الوصول: |
https://doaj.org/article/b0632c6c599e422eadabd6a0186dda22 |
| رقم الانضمام: |
edsdoj.b0632c6c599e422eadabd6a0186dda22 |
| قاعدة البيانات: |
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