التفاصيل البيبلوغرافية
| العنوان: |
Risk Factors and Establishment of Prediction Model for Preoperative Lymph Node Staging Deficiency in Gastric Cancer |
| المؤلفون: |
DU Shuxiang, GUO Zhen, CHEN Zilai, WANG Shangxin, WU Gang |
| المصدر: |
Zhongliu Fangzhi Yanjiu, Vol 50, Iss 5, Pp 498-504 (2023) |
| بيانات النشر: |
Magazine House of Cancer Research on Prevention and Treatment, 2023. |
| سنة النشر: |
2023 |
| المجموعة: |
LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: |
gastric cancer, thin-layer multistage enhanced ct, preoperative n-stage deficiency, risk factors, predictive model, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: |
Objective To analyze the risk factors of preoperative lymph node staging (N-stage) deficiency in gastric cancer and establish a preoperative assessment model to assist in predicting preoperative N-stage. Methods A retrospective method was used to analyze the clinicopathological data of 268 patients with gastric cancer. The patients routinely underwent preoperative thin-section enhanced CT to assess preoperative N-stage. Results The risk factors for preoperative N-stage deficiency were analyzed in combination with postoperative pathological findings. Multifactorial logistic regression analysis was performed to determine influencing factors, and Kaplan-Meier analysis was used to plot the survival curves of preoperative N-stage accurate group and deficiency group. The nomogram plot and ROC curves of the prediction model were drawn using the R package. AUC, 95%CI, sensitivity, and specificity were calculated. Results Age, BMI, poor differentiation, and Lauren's classification as diffuse were independent risk factors for preoperative N-stage deficiency in gastric cancer (P < 0.05). Prognostic survival was significantly worse in the preoperative N stage-inadequate group than that in the accurate group (P=0.041). The AUC area was 0.935, with a sensitivity of 85.9% and specificity of 96.9%. Conclusion Young age, high BMI, poor differentiation, and Lauren's classification as diffuse are independent risk factors for preoperative N-stage deficiency. The established preoperative assessment model based on age, BMI, differentiation degree, and Lauren's classification in this study has relatively high credibility. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
Chinese |
| تدمد: |
1000-8578 |
| Relation: |
http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2023.22.1254; https://doaj.org/toc/1000-8578 |
| DOI: |
10.3971/j.issn.1000-8578.2023.22.1254 |
| URL الوصول: |
https://doaj.org/article/c9fc57ea917145fbab8e055cfc623ff0 |
| رقم الانضمام: |
edsdoj.9fc57ea917145fbab8e055cfc623ff0 |
| قاعدة البيانات: |
Directory of Open Access Journals |