Academic Journal
Construction of tantalum/poly(ether imide) coatings on magnesium implants with both corrosion protection and osseointegration properties
| العنوان: | Construction of tantalum/poly(ether imide) coatings on magnesium implants with both corrosion protection and osseointegration properties |
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| المؤلفون: | Kwang-Hee Cheon, Cheonil Park, Min-Ho Kang, In-Gu Kang, Min-Kyu Lee, Hyun Lee, Hyoun-Ee Kim, Hyun-Do Jung, Tae-Sik Jang |
| المصدر: | Bioactive Materials, Vol 6, Iss 4, Pp 1189-1200 (2021) |
| بيانات النشر: | KeAi Communications Co., Ltd., 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Materials of engineering and construction. Mechanics of materials LCC:Biology (General) |
| مصطلحات موضوعية: | Magnesium, Tantalum, Poly(ether imide), Bio-functionalized coating, Biodegradable orthopedic implants, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5 |
| الوصف: | Poly(ether imide) (PEI) has shown satisfactory corrosion protection capability with good adhesion strength as a coating for magnesium (Mg), a potential candidate of biodegradable orthopedic implant material. However, its innate hydrophobic property causes insufficient osteoblast affinity and a lack of osseointegration. Herein, we modify the physical and chemical properties of a PEI-coated Mg implant. A plasma immersion ion implantation technique is combined with direct current (DC) magnetron sputtering to introduce biologically compatible tantalum (Ta) onto the surface of the PEI coating. The PEI-coating layer is not damaged during this process owing to the extremely short processing time (30 s), retaining its high corrosion protection property and adhesion stability. The Ta-implanted layer (roughly 10-nm-thick) on the topmost PEI surface generates long-term surface hydrophilicity and favorable surface conditions for pre-osteoblasts to adhere, proliferate, and differentiate. Furthermore, in a rabbit femur study, the Ta/PEI-coated Mg implant demonstrates significantly enhanced bone tissue affinity and osseointegration capability. These results indicate that Ta/PEI-coated Mg is promising for achieving early mechanical fixation and long-term success in biodegradable orthopedic implant applications. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2452-199X |
| Relation: | http://www.sciencedirect.com/science/article/pii/S2452199X20302589; https://doaj.org/toc/2452-199X |
| DOI: | 10.1016/j.bioactmat.2020.10.007 |
| URL الوصول: | https://doaj.org/article/9ecb0111e2984df3b09980cc3d872476 |
| رقم الانضمام: | edsdoj.9ecb0111e2984df3b09980cc3d872476 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2452199X |
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| DOI: | 10.1016/j.bioactmat.2020.10.007 |