Academic Journal
Spontaneous apoptosis and BCL2 gene expression as predictors of early death and short overall survival in acute leukemia patients: a prospective, case cohort study
| العنوان: | Spontaneous apoptosis and BCL2 gene expression as predictors of early death and short overall survival in acute leukemia patients: a prospective, case cohort study |
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| المؤلفون: | Huda F. Ebian, Lobna A. El-korashi, Ahmed Embaby, Marwa H. Hussien, Alshymaa A. Ahmed |
| المصدر: | Egyptian Journal of Medical Human Genetics, Vol 22, Iss 1, Pp 1-11 (2021) |
| بيانات النشر: | SpringerOpen, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine (General) LCC:Genetics |
| مصطلحات موضوعية: | Acute leukemia, Spontaneous apoptosis, BCL2, MCL1, BCL-XL, Medicine (General), R5-920, Genetics, QH426-470 |
| الوصف: | Abstract Background Spontaneous apoptosis and expression of MCL1, BCL2, and BCL-XL may be useful prognostic markers in acute leukemia patients. The purpose of this study is to examine the prognosis in adult leukemia patients based on spontaneous apoptosis and anti-apoptosis gene expressions in circulating leukocytes. Results Early, late, and total apoptosis were significantly increased in peripheral blood leukocytes from patients diagnosed with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) compared to controls and in cases of ALL versus AML (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2090-2441 |
| Relation: | https://doaj.org/toc/2090-2441 |
| DOI: | 10.1186/s43042-021-00210-8 |
| URL الوصول: | https://doaj.org/article/9e87f9dd685d40cd8e308b090086d22e |
| رقم الانضمام: | edsdoj.9e87f9dd685d40cd8e308b090086d22e |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20902441 |
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| DOI: | 10.1186/s43042-021-00210-8 |