التفاصيل البيبلوغرافية
| العنوان: |
Toward Multiplexed Optogenetic Circuits |
| المؤلفون: |
Ari Dwijayanti, Congqiang Zhang, Chueh Loo Poh, Thomas Lautier |
| المصدر: |
Frontiers in Bioengineering and Biotechnology, Vol 9 (2022) |
| بيانات النشر: |
Frontiers Media S.A., 2022. |
| سنة النشر: |
2022 |
| المجموعة: |
LCC:Biotechnology |
| مصطلحات موضوعية: |
multiplexed regulation, optogenetic circuits, light-sensitive proteins, engineered photoreceptor modules, biotechnological applications, metabolic engineering, Biotechnology, TP248.13-248.65 |
| الوصف: |
Owing to its ubiquity and easy availability in nature, light has been widely employed to control complex cellular behaviors. Light-sensitive proteins are the foundation to such diverse and multilevel adaptive regulations in a large range of organisms. Due to their remarkable properties and potential applications in engineered systems, exploration and engineering of natural light-sensitive proteins have significantly contributed to expand optogenetic toolboxes with tailor-made performances in synthetic genetic circuits. Progressively, more complex systems have been designed in which multiple photoreceptors, each sensing its dedicated wavelength, are combined to simultaneously coordinate cellular responses in a single cell. In this review, we highlight recent works and challenges on multiplexed optogenetic circuits in natural and engineered systems for a dynamic regulation breakthrough in biotechnological applications. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2296-4185 |
| Relation: |
https://www.frontiersin.org/articles/10.3389/fbioe.2021.804563/full; https://doaj.org/toc/2296-4185 |
| DOI: |
10.3389/fbioe.2021.804563 |
| URL الوصول: |
https://doaj.org/article/9e06c44519314913b143b7647ebf536a |
| رقم الانضمام: |
edsdoj.9e06c44519314913b143b7647ebf536a |
| قاعدة البيانات: |
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