التفاصيل البيبلوغرافية
| العنوان: |
A single dose of recombinant VSV-∆G-spike vaccine provides protection against SARS-CoV-2 challenge |
| المؤلفون: |
Yfat Yahalom-Ronen, Hadas Tamir, Sharon Melamed, Boaz Politi, Ohad Shifman, Hagit Achdout, Einat B. Vitner, Ofir Israeli, Elad Milrot, Dana Stein, Inbar Cohen-Gihon, Shlomi Lazar, Hila Gutman, Itai Glinert, Lilach Cherry, Yaron Vagima, Shirley Lazar, Shay Weiss, Amir Ben-Shmuel, Roy Avraham, Reut Puni, Edith Lupu, Elad Bar-David, Assa Sittner, Noam Erez, Ran Zichel, Emanuelle Mamroud, Ohad Mazor, Haim Levy, Orly Laskar, Shmuel Yitzhaki, Shmuel C. Shapira, Anat Zvi, Adi Beth-Din, Nir Paran, Tomer Israely |
| المصدر: |
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
| بيانات النشر: |
Nature Portfolio, 2020. |
| سنة النشر: |
2020 |
| المجموعة: |
LCC:Science |
| مصطلحات موضوعية: |
Science |
| الوصف: |
Here, the authors generate a replication-competent VSV based vaccine expressing SARS-CoV-2 spike protein and show protection in the hamster model with one dose. Analysis of the antibody response in mice shows induction of neutralizing antibodies and suggests a desirable Th1-biased response to the vaccine. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-020-20228-7 |
| URL الوصول: |
https://doaj.org/article/c9dbfd8736364f25b7884f0d5634e9e1 |
| رقم الانضمام: |
edsdoj.9dbfd8736364f25b7884f0d5634e9e1 |
| قاعدة البيانات: |
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