التفاصيل البيبلوغرافية
| العنوان: |
Co-administration of exercise training and melatonin on the function of diabetic heart tissue: a systematic review and meta-analysis of rodent models |
| المؤلفون: |
Afshin Rahbarghazi, Karim Azali Alamdari, Reza Rahbarghazi, Hanieh Salehi-Pourmehr |
| المصدر: |
Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-33 (2023) |
| بيانات النشر: |
BMC, 2023. |
| سنة النشر: |
2023 |
| المجموعة: |
LCC:Nutritional diseases. Deficiency diseases |
| مصطلحات موضوعية: |
Diabetes mellitus, Melatonin, Exercise, Cardiac tissue, Therapeutic effects, Nutritional diseases. Deficiency diseases, RC620-627 |
| الوصف: |
Abstract Purpose Diabetes mellitus (DM), a hyperglycemic condition, occurs due to the failure of insulin secretion and resistance. This study investigated the combined effects of exercise training and melatonin (Mel) on the function of heart tissue in diabetic rodent models. Methods A systematic search was conducted in Embase, ProQuest, Cochrane library, Clinicaltrial.gov, WHO, Google Scholar, PubMed, Ovid, Scopus, Web of Science, Ongoing Trials Registers, and Conference Proceedings in July 2022 with no limit of date or language. All trials associated with the effect of Mel and exercise in diabetic rodent models were included. Of the 962 relevant publications, 58 studies met our inclusion criteria as follows; Mel and type 1 DM (16 studies), Mel and type 2 DM (6 studies), exercise and type 1 DM (24 studies), and exercise and type 2 DM (12 studies). Meta-analysis of the data was done using the Mantel Haenszel method. Results In most of these studies, antioxidant status and oxidative stress, inflammatory response, apoptosis rate, lipid profiles, and glucose levels were monitored in diabetic heart tissue. According to our findings, both Mel and exercise can improve antioxidant capacity by activating antioxidant enzymes compared to the control diabetic groups (p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1758-5996 |
| Relation: |
https://doaj.org/toc/1758-5996 |
| DOI: |
10.1186/s13098-023-01045-6 |
| URL الوصول: |
https://doaj.org/article/9cf6deca2b1a4a5d8aab6e3b877a9cea |
| رقم الانضمام: |
edsdoj.9cf6deca2b1a4a5d8aab6e3b877a9cea |
| قاعدة البيانات: |
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